Chapter 17: Sex

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Genetic Sex

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Sex and the Brain

70 Terms

1

Genetic Sex

Genotype based on chromosomes

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2

Gender Identity

Self-perception of gender

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3

Sexual Orientation

the sex of whom one is physically attracted

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4

Concepts of biological sex and gender

– Biological characteristics and qualities

– Gender-specific behaviors

– Gender identity

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5

def 4 Gender-specific behaviors

  1. Introspection

    1. Upbringing

  2. Societal expectations

  3. Genetics, hormones

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6

X chromosome _____ than Y

larger

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7

X contains ___ genes, and Y contains __ genes.

800, 50

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8

male and female genotype

male: XY

female: XX

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9

X-linked diseases occur more often in… than…

men, women

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10

What makes fetus develop as male

SRY: gene on Y chromosome

  • Encodes testis-determining factor (TDF)

  • Causes the development of testes and testicular hormones

<p>SRY: gene on Y chromosome</p><ul><li><p>Encodes testis-determining factor (TDF)</p></li><li><p>Causes the development of testes and testicular hormones</p></li></ul>
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11

what causes Sex Chromosome Abnormalities

Rarely, too few, or too many sex chromosomes

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12

def turner syndrome

Partial or complete absence of one X chromosome in a female (XO genotype)

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13

def Klinefelter syndrome

Extra X chromosome in a male (XXY genotype)

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14

Differentiation of Fetus and Development of Gonads

male: wolffian duct

female: Mullerian duct

<p>male: wolffian duct</p><p>female: Mullerian duct</p>
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15

def sex hormones

steroids

  • develop from cholestoral

  • made of fatty tissue

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16

male and female sex hormones

male: testosterone

female: estradiol

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17

what releases sex hormones

endocrine glands

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18

what regulates the endocrine glands

Pituitary gland

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19

high concentration of androgens

men

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20

high concentration of estrogens

women

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21

how is estrogen made

Testosterone (androgen) + aromatase → estradiol (estrogen)

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22

what don’t pass through cell membranes,

bind surface receptors.

protein hormones

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23

what do pass through cell membrane, bind to

cytoplasmic receptors.

steroid hormones

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24

Receptor concentrations ___ in different brain regions.

vary

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25

what do testes release

androgen

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26

Testosterone increase at puberty leads to development of…

secondary sex characteristics.

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27

what do ovaries secrete

estradiol (estrogen) and progesterone (progestin)

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28

Estrogen increase at puberty leads to maturation of… and development of…

maturation of female reproductive system and development of breasts.

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29

Blood concentrations of sex hormones vary b/t male and female

male: levels fluctuate rapidly each day

female: levels fluctuate in 28-day cycle

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30

Gonadotropins

LH and FSH

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31

LH and FSH funct. in males

LH stimulates testosterone production; FSH aids sperm maturation

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32

LH and FSH funct. in females

LH and FSH cause estrogen secretion.

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33

def 2 phases of Menstrual cycle

  1. follicular phase

  2. luteal phase

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34

Sexual response cycle

Arousal, plateau, orgasm, resolution

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35

Cerebral cortex ctr Reproductive Organs

– Neural control of sexual response

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36

Spinal cord ctr Reproductive Organs

– Mediates sexual response of genitals

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37

External genitals

males: penis

females: labia and clitoris

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38

what kind of muscles make up genitals

smooth muscle

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39

what relaxes smooth muscle in penis and

clitoris

Neurotransmitters: Acetylcholine, vasoactive intestinal polypeptide (VIP), and nitric oxide (NO)

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40

Activity from the sympathetic division of the ANS

Male orgasm: muscular contractions → ejaculation

females orgasm: muscular contraction

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41

Polygyny

Male mates with many females.

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42

Polyandry

Female mates with many males.

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43

Monogamy

Male and female mate exclusively.

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44

why are prairie voles social and monogamous

more oxytocin (female) and vasopressin (male)

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45

what are montane voles asocial and promiscuous

fewer receptors for oxytocin and vasopressin

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46

what do human plasma oxytocin levels increase

  • During breastfeeding in mothers

  • During sexual intercourse in men and women

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47

Brain activation demonstrates…

strong reinforcing nature of partner and parental relationships.

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48

what do fMRI studies show

Oxytocin and vasopressin play roles in human bonding.

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49

who is more verbal and who is more spacial

women, men

*Larger differences between individuals than between sexes*

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50

Steroids funct

  • Alter membrane excitability, sensitivity to neurotransmitters, neurotransmitter release

  • Modulate functions of various enzymes, channels, and transmitter receptors

  • Diffuse across outer cell membrane

  • Bind to specific steroid receptors in cytoplasm and nucleus

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51

Organizational effects of hormones

  • Development, anatomy

  • Tend to be irreversible

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52

Activational effects of hormones

  • Behaviors

  • Tend to be temporary

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53

what normally determines hormonal funct.

genetic sex

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54

Treatment with testosterone in early development of mammals leads to

reduced female reproductive behaviors

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55

what causes an Androgen-insensitive genetic males

defective androgen gene on X chromosome

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56

what causes Congenital adrenal hyperplasia in genetic females

abnormally large adrenals overproduce androgens → External genitals intermediate between normal clitoris and penis

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57

def Gynandromorph

having both male and female tissues

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58

Gynandromorphic zebra finch - brain differences

Female left side

Male right side

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59

Role of genes in complex sex behaviors in fruit flies

  • Sexual behaviors encoded in genes

  • The fru and dsx genes

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60

what causes increased sexual interest - male vs female

  • male: rise in testosterone

  • Women: rise in estrogen

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61

what rises during pregnancy

Rise in leptin levels

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62

how does interaction with offspring may alter male brain structure

  • increase density of dendritic spines

  • Increased vasopressin receptors

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63

what has dramatic effects on hippocampal neuronal dendrites

Estradiol treatment

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64

what coincides with female rat’s peak fertility

Increase in hippocampal spine numbers

  • May play a role in changing reproductive needs

  • Estradiol’s protective effect on neurons (in culture)

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65

def 2 benefits of estrogen

  • May protect against stroke

  • May benefit women with multiple sclerosis

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66

Interstitial nucleus of the anterior hypothalamus (INAH); INAH-3 is Twice as large in… than…

men, women

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67

• INAH-3 in… similar to that in…

gay men, women

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68

Spinal nucleus of the bulbocavernosus (SNB) larger in… during…

men, erections

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69

Corpus callosum: splenium larger in… than…

females, males

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70

dimorphisms are

subtle, few, and functions unknown.

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