Helicobacter pylori

shape

spiral

Gram stain

Gram negative

necessary oxygen level

microaerophilic

where it’s found in infected people

stomach and duodenum

infection effects

gastric inflammation and ulcers

Helicobacter pylori increases the risk of _____ and _____ by ___

gastric cancer; tissue lymphoma; 80%

symptoms

generic- pain, nausea, vomiting, etc.

where it’s naturally found

human oral cavity and sheep

how many people get infected

2/3 of all people

how it’s passed from person to person

saliva, vomit, fecal matter

how it’s passed form environment to people

contaminated food and water

virulence factors definition

a pathogen’s ability to infect

virulence factors of Helicobacter pylori

colonizes the stomach and induces DNA breaks in epithelial cells

how it colonizes the stomach

increasing stomach pH and attaching to epithelial lining

effects of DNA breaks

mutations which lead to cancer cells

______ introduced the idea the ulcers were caused by infections

Robin Warren

_____ proved bacteria caused ulcers by performing Koch’s postulates on himself

Barry Marshall

treatment

antibiotics for infection and proton pump for symptoms

when must infection be treated

before it mutates DNA