GI system - unit 3

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What s the role of the GI tract/alimentary canal?

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1

What s the role of the GI tract/alimentary canal?

route of intake for nourishment, digest and absorb nutrients, eliminates waste products

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2

What are the accessory organs of the GI system?

salivary glands, pancreas, liver, gallblader

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3

What are the indications for a salivary gland imaging procedure?

eval of dry mouth (xerostomia)

rule out blockage of one or several glands/ducts

evaluate palpable mass

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4

What is the patient prep for a salivary gland procedure?

none

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5

What type of collimator is used for a salivary gland procedure?

low energy, parallel hole collimator

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6

How is the patient positioned for a Salviary gland procedure?

seated, facing the camera

head tilted backward with neck extended

chin resting on camera

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7

Why do we position the patient with their head tilted back in a salivary gland imaging procedure?

to prevent the thyroid from obscuring the salivary glands

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8

why do we give the patient lemon juice during a salivary gland imaging procedure? What types of images are we taking after this?

gustatory stimulation

20-minute flow images of tracer clearance from the salivary gland

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9

What is a general normal finding on a salivary gland imaging procedure?

simultaneous, rapid, and symmetrical uptake of all three glands

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10

What are some abnormal findings on a salivary gland image, and what is the cause of each?

hot spots/area of increased uptake = Warthin tumors

cold areas = metastatic lesions

poor response to gustatory stimulation = blockage

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11

Where is the esophagus located?

posterior to the trachea

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12

What are the three parts of the esophagus? What type of muscle is in each?

upper third = striated

middle = combination of striated and smooth

lower third = smooth

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13

What is the dosage for a salivary gland imaging procedure? How is it given?

1-5 mCi Tc-99m pertechnetate via IV

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14

What is the method of uptake of Tc-99m pertechnetate into the salivary glands?

ions are excreted by glands into saliva

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15

What images are taken in a salivary gland imaging procedure? How long are we taking these images for?

dynamic images of the anterior face and neck

1-2 second intervals for 15-20 seconds

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16

what are we looking for in salivary gland initial dynamic imaging?

simultaneous and symmetrical uptake

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17

What additional images are we taking for a salivary gland imaging procedure? And why are we taking these photos?

anterior and lateral views of the head and neck

confirming the normal presence of tracer in the saliva in the oral cavity

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18

What are normal findings for a salivary gland imaging procedure after the first swallow?

rapid decrease in esophageal activity within 5-10 seconds after first swallow

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19

What are normal findings for a salivary gland imaging procedure after 2 minutes?

at 2 min 10% of peak activity remains

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20

What are normal findings for a salivary gland imaging procedure after 10 minutes?

less than 5% of peak activity remains

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21

What are abnormal findings on a salivary gland imaging procedure?

any sort of delay - anything in esophageal track after 2 and 10 min

activity present in esophagus

Achalasia - absence of relaxation of the lower esophageal sphincter

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22

What are the indications for a Esophageal transit procedure?

esophageal motor disorder

efficacy of surgical or mechanical interventions on the lower esophagus

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23

What is an esophageal motor disorder?

difficulty or pain associated with swallowing

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24

What is the patient prep for a Esophageal transit procedure?

NPO for 2 hours

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25

What does NPO mean?

nothing per oral - aka no eating or drinking

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26

What is the dose for an Esophageal transit procedure?

300uCi of Tc-99m sulphur colloid

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27

How is the dose for an Esophageal transit procedure given?

in 15ml of tap water (orally)

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28

What type of collimator is used for a Esophageal transit procedure?

low energy, all purpose

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29

How is the camera positioned over the patient during an Esophageal transit procedure?

entire esophagus with the stomach at the bottom of the FOV

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30

What types of images are we taking for an Esophageal transit procedure? How long is each image taken?

flow/dynamic for total of 10 min

0.25 sec for first 2 min

15 sec intervals for 8 min

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31

How should the patient be instructed during an Esophageal transit procedure?

Pt should take entire dose/water in mouth but not swallow until instructed

have Pt swallow every 15 sec for 10 min

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32

What is gastroesophageal reflux?

complex symptoms including regurgitation of food/liquid, heartburn, and chest pain

gastric or duodenal contents enter the esophagus

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33

What can cause gastroesophageal reflux?

anatomic abnormalities, incompetence of the lower sphincter

fat, alcohol, chocolate, cigarettes

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34

What is the patient prep for a gastroesophageal reflux imaging procedure?

NPO for 8 hrs

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35

If an esophageal transit study is planned on the same day as a gastroesophageal reflux, which should be performed first?

esophageal transit study first

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36

What is the dose for a gastroesophageal reflux imaging study?

300uCi of Tc-99m Sulphur colloid

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37

How is the patient given the dose for a gastroesophageal reflux procedure?

300uCi of Tc-99m sulphur colloid, mixed with 150ml of orange juice and 150ml of 0.1 M hydrochloric acid

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38

Why is the dose for a gastroesophageal reflux procedure mixed with orange juice and hydrochloric acid?

acidity stimulates gastric reflux

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39

What is the estimated amount of fluid we give patients for a gastroesophageal reflux scan?

300ml or 10oz

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40

What are the four factors required to induce gastroesophageal reflux?

oral administration of acidified solution

successive, increased pressure applied to the abdomen

maintenance of supine position

at least 300ml volume in the stomach to oppose the applied pressure

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41

Describe the imaging procedure for a gastroesophageal reflux scan?

give patient dose

fit patient with an abdominal binder

10min after tracer administration begin imaging

position patient supine, w/ stomach at bottom of FOV (including entire stomach

  • if esophagus visualized during positioning give patient water to flush esophagus

acquire images for 30 seconds at the pressure points 0,20,40, 60, 80, 100mHg, without deflating between points

take post deflation image

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42

What are normal and abnormal findings for a gastroesophageal reflux study for adults?

normal = <4% reflux

abnormal = > 4% reflux and can be visualized in the images

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43

Why would 24 hr delayed images be performed on a gastroesophageal reflux study?

detection of pulmonary aspiration

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44

What types of findings might you see in a child/infant gastroesophageal reflux study? What dosage do we give to pediatric patients?

shows aspiration, or GER caused by delayed emptying

1mCi of Tc-99m Sulfur colloid in infant formula orally via NG or g-tube

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45

What is the role of the stomach in the digestive system?

food reservoir

breaks down solid food into chyme

controls rate of emptying gastric content into the duodenum

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46

Where does the stomach empty into?

duodenum into small intestine

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47

What is the top portion of the stomach?

fundus

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48

What is the lower region of the stomach before it empties into the small intestine? What is the valve that controls the rate of emptying?

pylorus

pyloric sphincter

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49

What is the patient prep for a gastric emptying procedure?

NPO 4-12 hrs before

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50

What are the indications for a gastric emptying procedure?

confirm gastroparesis as a cause of persistant nausea and vomiting

monitor effects of therapy in patients with abnormal motility - diabetics

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51

What are some factors that affect a gastric emptying procedure?

sex, time of day, composition of meal (volume, caloric content, amount, protein)

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52

What is gastroparesis?

delayed gastric emptying, food staying in stomach and not emptying

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53

What is the dose for a gastric emptying procedure? What are we giving to the patient? How fast should the meal be eaten?

1mCi of Tc-99m Sulfur colloid in eggs (scrambled, liquid), oatmeal

2 slices of white toast, 2 containers of jelly, 200ml of water

should be eaten in 10 min

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54

What are the pediatric tracer(s) used for a gastric emptying study? How is it given?

Tc-99m DTPA in formula, can also do In-111 DTPA in OJ

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55

What is the procedure for a gastric emptying study?

have patient eat breakfast within 10 min, immediately lay down under the camera(sometimes upright)

tape C0-57 marker right of xiphoid process

initial 45min dynamic study, then by 1 min static at 2, 3, and 4 hours post meal

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56

How long are we imaging/taking images in the initial dynamic image phase for a gastric emptying study? and when do we begin imaging?

1 min dynamic images for 45 minutes after patients meal

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57

If we graph the behavior of solids in a gastric emptying study, what type of behavior should we expect to see? What is the normal half-time for solids and why?

linear, 90min half time

3 textures all processed differently in body

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58

If we graph the behavior of liquids in a gastric emptying study, what type of behavior should we expect to see? What is the normal half-time for liquids?

exponential

half time = 30min

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59

What is the gastric emptying half time? What is it used for?

time it takes for the stomach to empty 50% of ingested meal

used to assess gastric transit

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60
<p>This gastric emptying graph demonstrates: </p>

This gastric emptying graph demonstrates:

normal liquid emptying

normal/slightly delayed solid emptying

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61
<p>This gastric emptying graph demonstrates: </p>

This gastric emptying graph demonstrates:

normal liquid emptying

delayed solid emptying

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62
<p>This gastric emptying graph demonstrates: </p>

This gastric emptying graph demonstrates:

delayed liquid emptying

delayed solid emptying

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63

what is a GI bleed?

blood loss from any organ in the GI tract (mouth to anus)

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64

Where does an upper GI bleed ordinate from? What can be a telltale indicator that it’s an upper GI bleed?

esophagus, stomach, duodenum (first part of small intestine)

dark, tarry stools

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65

Where does a small bowel bleed orignate from?

jejunum, ileum

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66

Where does a lower GI bleed originate from? What can be a telltale indicator that it’s a lower GI bleed?

colon, rectum, anus

bright red blood

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67

What are the indications for a GI bleed?

localization of the site of bleeding -active or intermittent

detecting and localization of hemorrhage including retroperitoneal and peripheral locations

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68

Is a GI bleed study usually an emergency procedure? why or why not?

prompt therapy depends on exact localization

usually substantial bleeding in stool

patient can bleed out - find cause to fix in surgery

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69

Is there any patient prep for a GI bleed scan?

no

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70

Are we performing static or dynamic images for a GI bleed?

dynamic to catch the bleed and localize the source of it

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71

What type of radiopharmaceuticals are we using for a GI bleed?

Tc-99m Sulfur colloid

Tc-99m labeled red blood cells

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72

What are the pros and cons of using tc 99m sulfur colloid for a GI bleed?

pros: minimizes background activity, promotes high contrast ratio

cons - rapid clearance, requires pt to be actively bleeding

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73

List the three ways we can label red blood cells for a GI bleed using Tc-99m.

in Vivo

in Vivi/in vitro

in vitro

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74

How are RBCs labeled in vivo for a GI bleed?

What is the general efficiency of using this method?

labeled inside body

inject stannous ion (Sn+2), wait 20-30 min, inject Tc-99m Pertechnetate

variable, 60-90% labeling efficiency

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75

What are the pros of performing a GI bleed scan in Vivo? What are the cons and why?

convenient and easy

can’t see bleeding in the stomach, small bowel, and/or colon because they’re natural areas of uptake of free Tc99m in body

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76

What is the procedure for an in VIvo/In vitro Gi bleed procedure? What is the efficiency rate of labeling?

IV injection of stannous ion

blood sample collected in syringe containig Tc-99m-pertechnetate and anticoagulant (heparin)

reinject labeled sample

~95% efficiency

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77

What are the pros of doing a Tc99m RBC labeled GI bleed procedure in vivo/In vitro?

absence of blood manipulation -less risk of mix ups

low risk of contamination

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78

What is the procedure for an In Vitro GI bleed procedure?

labeling done outside of body, small sample of blood (1-3ml) withdrawn into syringe containing anticoagulant heparin

let sit for 5 min

add sodium hypochlorite and ACD and. Tc-99m pertechnetate

wait 20 min, then inject into patient

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79

Why is in vitro the preferred labeling method for a GI bleed labeled RBC procedure?

high labeling efficiency, superior imaging quality

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80

What type of collimator are we using for a Tc-99m pertechnetate labeled RBC GI bleed procedure?

low energy, parallel hole collimator

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81

how is the patient positioned under the camera for a labeled RBC GI bleed procedure?

supine, often on a stretcher

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82

What anatomy should be included on a GI bleed labeled RBC procedure?

inferior margin of the liver at the top of the FOV

aka Xiphoid process to bladder should be in view

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83

Tc-99m Sulpfur colloid is better for what type of GI bleed?

an active bleed

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84

Which is the preferred tracer for a GI bleed procedure, Tc-999m sulfur colloid or Tc-99m labeled RBCs?

Tc-99m labeled RBCs

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85

What is the dose for Tc-99m Sulfur colloid for a GI bleed?

7-10 mCI

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86

What types of images are being taken for a Tc-99m sulfur colloid GI bleed procedure? What should be done if the GI bleed is not visualized during these initial images

dynamic for 2-3 min

static images ever 1-2 min for 30 min

should take specified count image of upper abdomen

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87

What are the downsides of using Tc-99m Sulfur colloid for a GI bleed procedure?

has rapid clearance, and only good for active bleed

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88

What is the dose for Tc-99m labled RBCs in a GI bleed?

10-15 mCi

up to 30 mCi

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89

What types of images are we taking for a tc99m sulfur colloid GI bleed procedure? Based on what parameter do we use when determining how long to image a patient?

initial flow images for 32 frames

dynamic images 1/min if bleed not visualized

basically keep imaging until you see something`

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90

Why is Tc99m labled RBCs the prefered method?

allows for imaging up to 36 hrs, possible delayed images

lower radiation dose to liver and spleen

preferred for intermittent bleeding

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91

What are the normal areas of uptake using Tc-99m Labled RBCs in a GI bleed procedure?

great vessels of the abdomen, liver, sometimes spleen depending on how well tagged

general outline of kidneys, bladder, small and large intestines, and genital organs

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92

What are the findings using Tc-99m sulfur colloid GI bleed procedure?

positive bleed within 5 min

focal areas

false positives in renal transplant pt due to accumulated tracer

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93

What are the findings using Tc-99m labled RBCs in a GI bleed procedure?

focal areas gradually become more intense

if first pictures are negative use delayed images

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94

What are some general things to be aware of in a GI bleed procedure?

patient in critical condition, keep an eye on them

smell = likely positive

catheter needs to be moved out of FOV

start imaging THEN inject patient

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95

What is a Meckel Diverticulum? What age is it most commonly found in?

pouch on wall of intestines that is present at birth (congenital) often contains gastric mucosa

children

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96

What are some symptoms of a Meckel Diverticulum?

abdominal pain

bloody stools

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97

What are some complications of Meckel Diverticulum?

peptic ulceration

hemorrhage from acid excretion (rupture/tearing)

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98

What is the patient prep for a Meckel Diverticulum imaging procedure?

NPO for 12 hrs

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99

What is the dose for Meckel Diverticulum?

10-15 mCi of tc-99m pertechnetate

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100

How is the camera positioned over the patient for a Meckel Diverticulum imaging procedure?

xiphoid to bladder

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