Transcription Regulation

Flashcards about transcription regulation in eukaryotes.

Proteins with helix-turn-helix motif, or with zinc-finger motif both motifs have _.

DNA-binding property

_ is the transcriptional activator protein required for transcription of GAL1, GAL7 and GAL10.

Gal4p

_ is a protein that binds to the transcriptional activation domain of Gal4 in the nucleus and prevents formation of a transcription complex.

Gal80p

_ is a cytoplasmic protein that, in the presence of galactose, binds Gal80p and prevents its entry into the nucleus

GAL3p

_ are DNA sequences where some activators bind.

Enhancers

_ are DNA sequences where a repressor binds.

Silencers

Basal TFs include , , , , ,

TFIIB, TFIID, TFIIE, TFIIH, TFIIF, TFIIA

_ are multiprotein complexes that restructure the chromatin.

Chromatin-remodeling complexes (CRCs)

Some eukaryotic genes have more than one promoters to allow for _.

differential regulation

_ causes transcriptional inactivation.

DNA methylation

_ causes varied effects on transcription.

Histone modification

_ means that the same transcript can be spliced differently.

Alternative splicing

RNAs that are transcribed but do not code for a protein are called _.

Non-coding RNAs

_ is a perfect double helical RNA, formed by transcripts of both strands of a DNA double helix.

siRNA (small interfering RNA)

_ is an imperfectly paired hairpin formed by single-stranded RNA containing an inverted repeat.

miRNA (microRNA)

Transcription uses the _ strand of DNA as a template.

antisense

Functions in the nucleus or cytoplasm, are mostly transcribed, spliced, 5’-capped and polyadenylated, and are implicated in epigenetic modification of gene expression are characteristic of _.

Long intergenic noncoding RNAs