top drugs briggs

amlodipine

limited human data- animal data suggest moderate risk

nifedipine

human data suggest low risk

benazepril

human data suggest risk in 2nd and 3rd trimester

lisinopril

human data suggest risk in 2nd and 3rd trimesters

chlorthalidone

compatible

hydrochlorothiazide

compatible

irbesartan

human data suggest risk in 2nd and 3rd trimesters

losartan

human data suggest risk in 2nd and 3rd trimesters

olmesartan

human data suggest risk in 2nd and 3rd trimesters

valsartan

human data suggest risk in 2nd and 3rd trimesters

hydrochlorothiazide, losartan

human data suggest risk in 2nd and 3rd trimesters

hydrochlorothiazide, lisinopril

human data suggest risk in 2nd and 3rd trimesters

amlodipine, benazepril

human data suggest risk in 2nd and 3rd trimesters

triamterene, hydrochlorothiazide

human data suggest risk in 2nd and 3rd trimesters

prazosin

limited human data

carvedilol

risk in 2nd and 3rd trimester

furosemide

low risk

metoprolol

human data suggest risk in 2nd and 3rd trimesters

atenolol

human data suggest risk in 2nd and 3rd trimesters

propranolol

human data suggest risk in 2nd and 3rd trimesters

spironolactone

limited human data- animal data suggest risk

hydralazine

human data suggest risk in 3rd trimester

clonidine

limited human data- animal data suggest risk

atorvastatin

contraindicated - 1st trimester

lovastatin

contraindicated - 1st trimester

pravastatin

weigh risks and benefits

rosuvastatin

weigh risks and benefits

simvastatin

weigh risks and benefits

insulin aspart

compatible

insulin lispro

compatible

insulin human (isophane human)

compatible

insulin degludec

compatible

insulin glargine

compatible

dulaglutide

no human data - animal data suggest risk

liraglutide

no human data - animal data suggest risk

semaglutide

not recommended - little data on effect

fenofibrate

limited human data- animal data suggest risk

gemfibrozil

limited human data - animal data suggest risk

dapagliflozin

no human data - animal data suggest low risk

empagliflozin

use should be avoided - 2nd & 3rd trimester

glimepiride

limited human data - animal data suggest risk

glipizide

limited human data - animal data suggest risk

ezetimibe

limited human data - animal data suggest moderate risk

pioglitazone

no human data- animal data suggest moderate risk

metformin

human data suggest low risk

sitagliptin

limited human data - animal data suggest low risk

metformin, sitagliptin

weigh risks and benefits

calcium phosphate, cholecalciferol

compatible

cholecalciferol

fetal risk cannot be ruled out; available evidence is inconclusive or inadequate for determining fetal risk when used in pregnant women.

cyanocobalamin

compatible

desogestrel; ethinyl estradiol

contraindicated

drospirenone; ethinyl estradiol

contraindicated

ergocalciferol

fetal risk cant be ruled out; larger doses than RDA should be avoided

estradiol (oral and transdermal patch)

contraindicated

ethinyl estradiol; etonogestrel

contraindicated

ethinyl estradiol; levonorgestrel

contraindicated

ethinyl estradiol; norethindrone

contraindicated

ethinyl estradiol; norgestimate

contraindicated

ferrous sulfate

compatible

folic acid

fetal risk is minimal

levothyroxine

compatible

liothyronine

minimal risk to fetus

norethindrone

hypersensitivity to any component of the product, Abnormal and undiagnosed genital bleeding, acute liver disease, benign or malignant liver tumors, carcinoma of the breast

potassium chloride

compatible

progesterone

weigh risks and benefits

testosterone

contraindicated

thyroid

compatible

acyclovir

compatible

amiodarone

human and animal data suggest risk

amoxicillin

risk in 1st and 3rd trimesters

amoxicillin/clavulanate

amoxicillin: contraindicated in 1st and 3rd trimesters

clavulanate: compatible

apixaban

potential risk

aspirin

compatible (low dose); human data suggest risk in 1st and 3rd trimesters (full dose)

azithromycin

compatible

cefdinir

compatible

cephalexin

compatible

ciprofloxacin (PO, otic)

contraindicated (PO); weigh risks and benefits (otic)

clindamycin (PO, topical)

compatible

clopidogrel

limited human data - probably compatible

dapagliflozin

no human data - animal data suggests low risk

diltiazem

low risk

doxycycline

contraindicated - 2nd and 3rd trimesters

fluconazole

risk

isosorbide mononitrate

limited human data - animal data suggest moderate risk

ketoconazole (topical)

probably compatible

metronidazole

human data suggest low risk

nitrofurantoin

risk in 3rd trimester

nitroglycerin

human data suggest low risk

oseltamivir phosphate

compatible-maternal benefit> embryo-fetal risk

rivaroxaban

moderate risk

sacubitril/valsartan

contraindicated

torsemide

no human data- probably compatible

trimethoprim/sulfamethoxazole

risk in 3rd trimester

valacyclovir

compatible

verapamil

compatible

warfarin

contraindicated- 1st trimester

albuterol

compatible

azelastine

compatible

budesonide

compatible

budesonide/formoterol

compatible (budesonide); limited human data- probably compatible (formoterol)