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Comprehensive vocabulary flashcards generated from lecture notes on tissue types, gland classifications, membrane structures, and tissue healing.
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Four types of tissues
Epithelial, connective, muscle, nerve
Epithelial Tissue
Sheets of cells that cover and line other tissues, functioning to protect core and line, filters biochemical substances, absorbs nutrients , provide sensory input, and manufacture secretions and excretions.
Characteristics of epithelia
Organized into tightly packed groups that form sheets, celli are polar, apical surface faces lumen or is exposed to outside world, basal surface is attached to basement membrane, lateral surface connects to neighboring cells, avascular, innervated (provide sensory info)
Tight Junctions
fusion of the outermost area of plasma membranes of adjoining cells to create a leak-proof seal.
Desmosomes
Strong mechanical couplings between cells involving plaque and tonofilaments, found in tissues undergoing repeated tension and stretching.
Gap Junctions
Cell junctions linked by tubular channel proteins called connexons that allow exchange of ions and nutrients and fast transport of electrical signals.
Basement Membrane
A nonliving, avascular network of fibers (also called basal lamina) serving as a foundation that cements epithelial cells to underlying tissue, varies in thickness, partial barrier to underlying tissue, allows diffusion of nutrients, waste
Apical surface specialization
Varies depending on epithelial location and role in the function of the tissue (smooth, microvilli, cilia, keratin)
Classification of epithelia
1) number of cell layers: simple, stratified
2)cell shape: squamous, cuboidal, columnar
3) presence of surface specialization: cilia, keratin
Simple Squamous Epithelium
A single layer of delicate, thin, flat, and smooth cells found lining surfaces involved in the passage of gas or liquid (lungs, kidneys), can have regional name (endothelium lines inside of vessel walls)
Stratified Squamous Epithelium
Multilayered, relatively flat epithelium that protects underlying tissues in areas subject to mechanical and chemical stresses (mouth, rectum), outer layer continually soughed away, replaced at equal rate by dividing cells in deeper layers, only stratum basale attached to basement membrane
Simple Cuboidal Epithelium
A single layer of cube-shaped cells with nuclei aligned in a single row, found in glandular ducts and renal tubules for secretion and absorption.
Simple Columnar Epithelium
Tall, elongated, closely packed cells with nuclei aligned at the base, associated with absorption and secretion in the GI tract.
Pseudostratified Columnar Epithelium
A single layer of epithelial cells with nuclei at varying levels that give the appearance of stratification, not all cells reach luminal surface but all cells attached to basement membrane, most are ciliated, located in respiratory tract and reproductive tract
Transitional Epithelium
Epithelium featuring a basal layer of cuboidal or columnar cells and a superficial layer that flattens when stretched, providing a leak-proof membrane in expandable regions (bladder)
Endocrine Glands
Multicellular glands that do not have ducts or tubules and secrete hormones directly into the bloodstream.
Exocrine Glands
Glands possessing ducts (except for unicellular goblet cells) that discharge secretions directly into local areas.
Goblet Cell
A unicellular exocrine gland modified from a columnar epithelial cell that secretes mucin.
Multicellular exocrine glands
Composed of a secretory unit and a duct
Merocrine Glands
Exocrine glands whose secretory cells remain intact while secretions are manufactured, packaged, and released via exocytosis.
Apocrine Glands
Glands that store their secretions and release the apical (top) aspect of the cell into the duct system.
Holocrine Glands
Glands that store their secretions and release the entire cell into the duct system.
Three types of secretion
Sebaceous (oily, waxy), serous (watery, high concentration of enzymes), mucous (thick, composed of glycoproteins, mixed endocrine glands
Connective Tissue
The most abundant tissue by weight, providing metabolic and structural connections, protection, insulation, energy storage, structural support, and transport, most is vascularized (fat, cartilage, bone)
Ground Substance
An amorphous, homogeneous medium in connective tissue through which cells exchange nutrients and waste with circulation.
Collagenous Fibers (type of extracellular fiber)
Strong, thick bundles composed of the protein collagen, located in varying densities in tendons and ligaments.
Reticular Fibers (extracellular fibers)
Thin, delicate, branched networks of collagen that provide structural support for cellular organs.
Elastic Fibers (extracullar fibers)
Networks of coiled microfibrils composed primarily of the protein elastin that occur in tissues subjected to stretching (vocal chords, lungs, skin)
Fixed Cells
Connective tissue cells that remain within the tissue and are involved in the production and maintenance of the extracellular matrix.
Transient Cells
Connective tissue cells (wandering cells) that move in and out of connective tissue by diapedesis to assist in immune response and repair.
Areolar Tissue (type of loose connective tissue)
The most common connective tissue in the body, consisting of a tangle of random fibers suspended in a thick ground substance high in hyaluronic acid, functions: surrounds and supports, provides nutrients found primarily in submucosal and subcutaneous layers, can be the side of edema, pitting edema
Adipose Tissue
A loose connective tissue that serves as an energy storehouse, thermal insulator, and mechanical shock absorber, it is fat, two main types are adipose and brown adipose
Reticular Tissue
Loose connective tissue composed of thin reticular fibers and fibroblasts that forms the framework (stroma) for organs.
Dense Regular Connective Tissue
Tightly packed parallel collagen fibers with rows of fibroblasts that form relatively avascular structures like tendons and ligaments.
Dense Irregular Connective Tissue
Thick collagen bundles interwoven into a single sheet with scattered fibroblasts, found in the dermis and organ capsules.
Elastic connective tissue
Type of dense connective tissue in body regions that require stretching, some ligaments, walls of arteries, stomach, bronchi, bladder, heart
What are the three types of specialized connective tissue
Cartilage (3 types), bone, blood
Cartilage
More rigid than dense connective tissue but more flexible than bone, no innervation and avascular, fixed cells are chondroblasts/chondrocytes, located in joint surfaces, ear, nose, vocal cords, framework for skeletal bone formation
Hyaline Cartilage
The most common and most rigid cartilage type, composed of closely packed collagen fibers enclosed within a perichondrium. Located in most of embryonic skeleton, tracheal rings, articular cartilage, growth plates of long bones
Elastic Cartilage
Flexible cartilage containing dense, branching bundles of elastic fibers that withstands repeated bending, epiglottis of larynx, external ears of animals (pinnae)
Fibrocartilage
designed to withstand strong compression forces, between vertebrae of spine (intervertebral discs), between bones in pelvis, stifle joint (meniscus)
Bone
The hardest and most rigid connective tissue, comprising an extracellular matrix of organic collagen fibers and inorganic calcium salts, fixed cells osteoblast/cyte, well vascularized and innervated, makes up the skeletal frame
Blood
Fluid connective tissue, extracellular matrix, ground substance is plasma (mostly water), fibrous component is proteins, erythrocytes are red, leukocytes are white, thrombocytes are platelets
What is a membrane and 4 common types
Thin, protective layers of tissues linked together and an epithelial sheet bound to underlying connective tissue. 4 types are mucous, serous, cutaneous, synovial
Mucous Membranes
Membranes lining organs with connections to the outside environment, consisting of an epithelial layer and an underlying lamina propria.
Serous Membranes
Membranes lining closed body cavities and organs, composed of a simple squamous epithelial sheet bound to loose areolar connective tissue.
Transudate
Normal, small amounts of watery serosal fluid produced in body cavities to reduce friction.
Effusion
Excessive production of fluid within a body cavity.
Exudate
Fluid containing abnormally high cell numbers or protein content, commonly produced during inflammation.
Cutaneous Membrane
The skin (integument), composed of an outer keratinized stratified squamous epithelium (epidermis) and an underlying dense irregular connective tissue layer (dermis).
Synovial Membranes
Specialized non-epithelial membranes lining joint cavities that produce and filter synovial fluid.
Skeletal Muscle
Voluntary, striated muscle tissue consisting of large multinucleate cells that attach to bone.
Smooth Muscle
Involuntary, nonstriated muscle tissue made of small, spindle-shaped single-nucleus cells located in the walls of hollow organs.
Cardiac Muscle
Involuntary, striated muscle tissue found only in the heart, consisting of branching single-nucleus cells connected by intercalated disks.
Neurons
The primary functional cells of nervous tissue designed to receive and transmit electrical signals, consisting of a perikaryon, dendrites, and an axon.
Neuroglial Cells
Supportive cells in nervous tissue that isolate, insulate, nourish, and protect neurons without transmitting impulses.
Inflammation
The initial nonspecific response to tissue injury aimed at limiting damage, characterized by vasoconstriction followed by vasodilation, edema, clot formation, and phagocytosis.
Granulation Tissue
Newly formed tissue during the organization step of healing, composed of newly branched capillaries and collagen fibers.
First-Intention Healing
Wound healing classification where the wound edges are in close apposition, resulting in minimal granulation tissue formation and scarring.
Second-Intention Healing
Wound healing classification where wound edges are separated, requiring granulation tissue formation and resulting in scarring.