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Pharynx
An area in the vertebrate throat where air and food passages cross.
Rectum
The terminal portion of the large intestine, where the feces are stored prior to elimination.
salivary gland
A gland associated with the oral cavity that secretes substances that lubricate food and begin the process of chemical digestion.
small intestine
The longest section of the alimentary canal, so named because of its small diameter compared with that of the large intestine; the principal site of the enzymatic hydrolysis of food macromolecules and the absorption of nutrients.
Sphincter
A ringlike band of muscle fibers that controls the size of an opening in the body, such as the passage between the esophagus and the stomach.
stomach
An organ of the digestive system that stores food and performs preliminary steps of digestion
villus (plural, villi)
A finger-like projection of the inner surface of the small intestine.
absorption
The third stage of food processing in animals: the uptake of small nutrient molecules by an organism's body.
Amylase
An enzyme that hydrolyzes starch (a glucose polymer from plants) and glycogen (a glucose polymer from animals) into smaller polysaccharides and the disaccharide maltose.
appendix
A small, finger-like extension of the vertebrate cecum; contains a mass of white blood cells that contribute to immunity.
bolus
A lubricated ball of chewed food.
cecum (sē′-kum) (plural, ceca)
The blind pouch forming one branch of the large intestine.
colon (kō′-len)
The largest section of the vertebrate large intestine; functions in water absorption and formation of feces.
chylomicron (kī′-lō-mī′-kron)
A lipid transport globule composed of fats mixed with cholesterol and coated with proteins.
chyme (kīm)
The mixture of partially digested food and digestive juices formed in the stomach.
digestion
The second stage of food processing in animals; the breaking down of food into molecules small enough for the body to absorb.
duodenum (dū′-uh-dēn′-um)
The first section of the small intestine, where chyme from the stomach mixes with digestive juices from the pancreas, liver, and gallbladder as well as from gland cells of the intestinal wall.
elimination
The fourth and final stage of food processing in animals: the passing of undigested material out of the body.
esophagus (eh-sof′-uh-gus)
A muscular tube that conducts food, by peristalsis, from the pharynx to the stomach
feces (fē′-sēz)
The wastes of the digestive tract.
gallbladder
An organ that stores bile and releases it as needed into the small intestine
gastric juice
A digestive fluid secreted by the stomach.
ingestion
The first stage of food processing in animals: the act of eating.
large intestine
The portion of the vertebrate alimentary canal between the small intestine and the anus; functions mainly in water absorption and the formation of feces.
lacteal (lak′-tē-ul)
A tiny lymph vessel extending into the core of an intestinal villus and serving as the destination for absorbed chylomicrons.
microvillus (plural, microvilli)
One of many fine, finger-like projections of the epithelial cells in the lumen of the small intestine that increase its surface area.
mucus
A viscous and slippery mixture of glycoproteins, cells, salts, and water that moistens and protects the membranes lining body cavities that open to the exterior.
oral cavity
The mouth of an animal.
pancreas (pan′-krē-us)
A gland with exocrine and endocrine tissues. The exocrine portion functions in digestion, secreting enzymes and an alkaline solution into the small intestine via a duct; the ductless endocrine portion functions in homeostasis, secreting the hormones insulin and glucagon into the blood.
peristalsis (pār′-uh-stal′-sis)
Alternating waves of contraction and relaxation in the smooth muscles lining the alimentary canal that push food along the canal.
Active immunity
long lasting immunity conferred by the action of B cells and T cells and resulting B and T memory cells specific for a pathogen. Results from natural infection or immunization
Adaptive immunity
A vertebrate specific defense that is mediated by B lymphocytes and T lymphocytes that exhibits specificity, memory and self-nonself recognition
Antibody
A protein secreted by plasma cells that binds to a particular antigen
antigen (an′-ti-jen)
A substance that elicits an immune response by binding to receptors of B or T cells.
B cells
The lymphocytes that complete their development in the bone marrow and become effector cells for the humoral immune response
cell-mediated immune response
The branch of adaptive immunity that involves the activation of cytotoxic T cells, which defend against infected cells
clonal selection
The process where an antigen selectively binds to and activates only those lymphocytes with receptors for specific antigens and they proliferate and differentiate into clones
complement system
a group of blood proteins that amplify the inflammatory response, enhance phagocytosis or directly lyse extracellular pathogens
cytotoxic T cells
A type of lymphocyte that, when activated, kills infected cells as well as certain cancer cells and transplanted cells.
Dendritic cells
An antigen-presenting cell that is particularly efficient in presenting antigens to helper T cells, thereby initiating a primary immune response
epitope
A small, accessible region of an antigen to which an antigen receptor or antibody binds.
helper T cell
A type of T cell that, when activated, secretes cytokines that promote the response of B cells and cytotoxic T cells to antigens
histamine
A substance released by mast cells that causes blood vessels to dilate and become more permeable in inflammatory and allergic responses
humoral immune response (hyū′-mer-ul)
The branch of adaptive immunity that in- volves the activation of B cells and that leads to the production of antibodies, which defend against bacteria and viruses in body fluids.
immunoglobulin
A protein secreted by plasma cells that binds to a particular antigen
inflammatory response
An innate immune defense involving the release of substances that promote swelling, white blood cells, and tissue repair
innate immunity
A form of defense common to all animals that is active immediately upon exposure to a pathogen
interferons
A protein that has antiviral or immune regulatory functions by helping nearby cells resist viral infection or helping to activate macrophages.
lymphocytes
A type of white blood cell that mediates immune responses. The two main classes are B cells and T cells
macrophages
A phagocytic cell present in many tissues that functions in innate immunity by destroying microbes and in acquired immunity as an antigen-presenting cell.
major histocompatibility complex
A host protein that functions in antigen presentation and can trigger T cell responses that may lead to rejection of a transplant.
mast cells
A vertebrate body cell that produces histamine and other molecules that trigger inflammation in response to infection and in allergic reactions.
memory cells
One of a clone of long-lived lymphocytes, that remains in a lymphoid organ until activated by exposure to the same antigen that triggered its formation.
monoclonal antibodies
Any of a preparation of antibodies that have been produced by a single clone of cultured cells and thus are all specific for the same epitope.
natural killer cells
A type of white blood cell that can kill tumor cells and virus-infected cells as part of innate immunity
neutrophils
The most abundant type of white blood cell that are phagocytic and tend to self-destruct as they destroy foreign invaders, limiting their life span to a few days.
passive immunity
Short-term immunity conferred by the transfer of antibodies, as occurs in the transfer of maternal antibodies to a fetus or nursing infant.
plasma cells
The antibody-secreting effector cell of humoral immunity that arise from antigen-stimulated B cells.
primary immune response
The initial adaptive immune response to an antigen, which appears after a lag of about 10-17 days.
secondary immune response
The rapid adaptive immune response elicited on second or subsequent exposures to a particular antigen that is of greater magnitude, and of longer duration.
T cells
The class of lymphocytes that include both effector cells for the cell-mediated immune response and helper cells required for both branches of adaptive immunity.
Thymus
A small organ in the thoracic cavity of vertebrates where maturation of T cells is completed.