meds without moves

(antiarrhythmics)

class/moa of flecainide and propafenone

Class I Antiarrhythmic: Sodium channel blockers, with Propafenone having a small beta blocker effect. Significant decrease in conduction velocity and automaticity.

FlecaiNide and propafeNoNe

class nad moa of ibutilide, dofetilide, dronedarone, amiodarone, sotalol

Class III Antiarrhythmic: Prolongation of the myocardial cell-action potential duration and refractory period, and noncompetitive alpha and beta inhibition. Blockade of Potassium channels.

whihc of the four classes of heart meds is the beta blockers

class 2 bb🤩

what class of heart meds are the Ca channel blockers like diltazem and verapamil

class 4

Flecainide brand

tambocor

Propafenone brand

rythmol

what is svt?

Supraventricular Tachycardia— atria contracts too fast

Flecainide box warning

Mortality, Ventricular proarrhythmic effects, MI

Propafenone box warning

Likely to cause arrhythmia , reserve for life-threatening arrhythmia

which class 1 (Na channel blocking) anti-arrth is renally adjusted

flecainide

flecainide, Propafenone ad eff

"Common: Palpitations, Nausea, Dizziness, Headache, Visual Disturbances (Taste Disturbances [Metallic Taste] – Propafenone)

Serious: Prolonged QT, Cardiac dysrhythmias"

which class 1 na channel blocker causes taste disturbances

Propafenone

flecainide, Propafenone ddi

"CYP2D6 inx

QT prolonging agents

Antiarrhythmics"

what two ddrugs/ what class of antiarrythkmic is “Used as pill-in-the-pocket for patient-initiated pharmacological cardioversion of A-fib”

flecainide, Propafenone (class 1)

which two class 3 antiarrythm have renal adjustment

dofetilide, sotalol

ibutilide indication

convert afib back into normal rhythm (cardioversion)

Dofetilide ind

"A-fib

Maintenance of NSR and cardioversion to NSR" (normal sinus rhythm)

which class three antirhyh are IV

Ibutilide, Amiodarone, Sotalol

which class three antiarrth are PO (can be both IV and PO)

Amiodarone

Sotalol

Dofetilide

Dronedarone

Ibutilide brand

Life-Threatening Arrhythmia, Confirm Benefit of Maintaining NSR Outweighs the Risk of Therapy

how is dofetidlide box warning related to LOCATION?

Initiate or reinitiate in the hospital

how are the Class III drugs different from one another

ibu/dofe: only K, dof more acute

drone/amiodarone: block Na, K, Ca channels and beta blocker

sotalol: K blocker and beta blocker

why dronedarone made?

“safer amiodarone”— no iodine so less thyroid toxciity

ibutilide ad eff

Serious: Bradyarrhythmia, Prolonged QT Interval (TdP), Hypotension, Headache

what is the acute Afib hospital converter?

ibutilide

dofetilide ad eff

"Common: Chest Pain, Dizziness, Headache

Serious: Prolonged QT, Ventricular Arrhythmias (TdP)"

dronedarone ad eff

"Common: N/V/D, Asthenia, abdominal pain

Serious: Increased SCr (Not Directly Nephrotoxic), QT Prolongation, Liver Failure, AKI, Heart failure"

what drug is basically all the class blockers (k, Na, Ca, b-blocker)

amiodarone

which heart med turns your skin blue

amiodarone

which heart drug can cause pulmonary fibrosis, hepatotoxcity, eye corneal deposits, and thyroid damage

amiodarone

amiodarone side effects

"Common: Hypotension, Bradycardia, Constipation, Nausea, Vomiting, Dizziness, Photosensitivity, Thyroid Dysfunction, Ataxia, Corneal Deposit, Blue-Gray Skin

Serious: Arrhythmias, Prolonged QT Interval, Pulmonary Fibrosis"

amiodarone ddi

"CYP1A2 inx

CYP2D6 inx

CYP3A4 inx

Digoxin (digoxin toxicity)

Increased levels of simvastatin and lovastatin

PGP inx

QT Prolonging Drugs

Warfarin (increased INR)

Bactrim (increased Bactrim)

Antiarrhythmics"

which class 3 blocker needs to be taken consistently with regard to meals

amiodarone

sotalol dose adjustment

renal

which class three is also a beta blocker

sotalol

sotalol brand name

betapace

when use amiodarone?

"Label :Ventricular arrhythmia

Off Label: A-fib"

(when like not responsive to other treatment)

sotalol when use

"Ventricular arrhythmia

Maintenance of NSR "

use commonly unless prolong QT or torsades de points, bradycardia

sotalol contraind

Bronchospastic Conditions, Sinus Bradycardia, 2nd and 3rd degree AV block (Unless Pacemaker), Long QT, Cardiogenic Shock, Uncontrolled CHF

sotalol side effects

Bronchospastic Conditions, Sinus Bradycardia, 2nd and 3rd degree AV block (Unless Pacemaker), Long QT, Cardiogenic Shock, Uncontrolled CHF

sotalol ddi

qt prolong

antiarrhytmic