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MEDICATION
It is a substance administered for the diagnosis, cure, treatment, or relief of a symptom or for prevention of disease.
also has the connotation of an illicitly obtained substance such as heroin, cocaine, or amphetamines.
prescription
The written direction for the preparation and administration of a drug is called a
1. GENERIC NAME
2. TRADE NAME
3. OFFICIAL NAME
4. CHEMICAL NAME
4 KINDS OF DRUG NAMES:
trade name
(sometimes called the brand name) is the name given by the drug manufacturer and identifies it as property of that company.
official name
is the name under which a drug is listed in one of the official publications
chemical name
is the name by which a chemist knows it; this name describes the constituents of the drug precisely.
Generic name
refers to the nonproprietary name given to a drug, by a pharmaceutical company.
nonproprietary
the name of the medicine is not patented, no intellectual property. For example, paracetamol
Generic name
Hyoscine butylbromide
______________ name
Chemical name
Hyoscine N-butylbromide
________name
Brand
Buscopan
__________ name
Pharmacology
is the study of the effect of drugs on living organisms.
Pharmacy
is the art of preparing, compounding, and dispensing drugs. The word also refers to the place where drugs are prepared and dispensed.
licensed pharmacist
prepares, makes, and dispenses drugs as ordered by a physician, dentist, nurse practitioner, or physician assistant.
PHARMACOPOEIA
is a book containing a list of products used in medicine, with descriptions of the product, chemical tests for determining identity and purity, and formulas and prescriptions.
therapeutic effect
- is the primary effect intended, that is, the reason the drug is prescribed.
- also referred to as the desired effect
1. Palliative
2. Curative
3. Supportive
4. Substitutive
5. Chemotherapeutic
6. Restorative
Therapeutic Actions of Drugs:
Palliative
- Relieves the symptoms of a disease but does not affect the disease itself.
- Morphine sulfate, aspirin for pain
Curative
- Cures a disease or condition.
- Penicillin for infection
Supportive
- Supports body function until other treatments or the body's response can take over.
- Norepinephrine bitartrate for low blood pressure; aspirin for high body temperature
Substitutive
- Replaces body fluids or substances
- Thyroxine for hypothyroidism, insulin for diabetes mellitus
Chemotherapeutic
- Destroys malignant cells.
- Busulfan for leukemia
Restorative
- Returns the body to health.
- Vitamin, mineral supplements
SIDE EFFECT
- are usually predictable and may be either harmless or potentially harmful.
- or secondary effect, of a drug is one that is unintended.
ADVERSE EFFECT
- more severe side effects
- reactions, may justify the discontinuation of a drug.
Drug toxicity
(harmful effects of a drug on an organism or tissue) results from overdosage, ingestion of a drug intended for external use, or buildup of the drug in the blood because of impaired metabolism or excretion (cumulative effect).
drug allergy
- is an immunologic reaction to a drug.
anaphylactic reaction
A severe allergic reaction usually occurs immediately after the administration of the drug and is called an
Drug tolerance
exists in a client who exhibits an unusually low physiologic response to a drug and who requires increases in the dosage to maintain a given therapeutic effect.
cumulative effect
is the increasing response to repeated doses of a drug that occurs when the rate of administration exceeds the rate of metabolism or excretion.
idiosyncratic effect
- is one that is unexpected and may be individual to a client.
- the drug may have a completely different effect from the normal one or cause unpredictable and unexplainable symptoms in a particular client.
drug interaction
occurs when the administration of one drug before, at the same time as, or after another drug alters the effect of one or both drugs.
1. Drug to drug
2. Drug to food
3. Drug to condition
Drug interaction has three:
beta-blocker
"olol" is _____________
calcium channel blocker
"dipine" is __________________
angiotensin receptor blocker
"sartan" is ________________________
POTENTIATING EFFECT
may be additive or synergistic
ADDITIVE
When two of the same types of drug increase the action of each other.
- occurs when two different drugs increase the action of one or another drug.
- For example, probenecid, which blocks the excretion of penicillin, can be given with penicillin to increase blood levels of the penicillin for longer periods (synergistic effect).
Iatrogenic disease
(disease caused unintentionally by medical therapy) can be a result of drug therapy.
DRUG MISUSE
is the improper use of common medications in ways that lead to acute and chronic toxicity.
- is the inappropriate intake of a substance, either continually or periodically.
- By definition, drug use is abusive when society considers it abusive.
1. drug dependence
2. habituation.
. Drug abuse has two main aspects:
Drug dependence
is the reliance on or need to take a drug or substance
1. PHYSIOLOGIC
2. PSYCHOLOGIC
The two types of drug dependence:
Physiologic dependence
- is due to biochemical changes in body tissues, especially the nervous system.
- These tissues come to require the substance for normal functioning.
PSYCHOLOGIC
is emotional reliance on a drug to maintain a sense of well-being, accompanied by feelings of need or cravings for that drug.
DRUG HABITUATION
- means a mild form of psychologic dependence.
- The individual develops the habit of taking the substance and feels better after taking it.
Illicit drugs
- also called street drugs, are those sold illegally.
- often are taken because of their mood-altering effect; that is, they make the user feel happy or relaxed.
1. NAME of the medication
2. AMOUNT or DOSAGE of the medication
3. ROUTE of administration
4. TIME of administration
5. SPECIAL or ADDITIONAL instructions
Essential Parts of a Medication Order:
1. stat order
2. single order or one-time order
3. standing order
4. prn order
TYPE OF MEDICATION ORDERS:
stat order
indicates that the medication is to be given immediately and only once (e.g., morphine sulfate 10 milligrams IV stat).
single order or one-time order
is for medication to be given once at a specified time (e.g., Seconal 100 milligrams at bedtime before surgery).
standing order
- may or may not have a termination date.
- may be carried out indefinitely (e.g., multiple vitamins daily) until an order is written to cancel it, or it may be carried out for a specified number of days (e.g., KCl twice daily x 2 days).
prn order
or as-needed order, permits the nurse to give a medication when, in the nurse's judgment, the client requires it (e.g., Amphojel 15 mL prn).
desired dose
D = _____________ (i.e., dose ordered by primary care provider)
dose on hand
H = ______________ (i.e., dose on label of bottle, vial, ampule)
vehicle
V = ____________ (i.e., form in which the drug comes, such as tablet or liquid).
DxV / H = amount to administer
Formula =
10 mL
Order: Erythromycin 500 mg
On hand: 250 mg in 5 mL
2 tablets
Order: Lanoxin (digoxin) 0.5 mg daily.
On hand: Lanoxin (digoxin) 250 mcg/tab
1. ORAL
2. SUBLINGUAL
3. BUCCAL
4. TOPICAL
5. PARENTERAL
ROUTE OF ADMINISTRATION:
oral, sublingual, topical, and parenteral.
The most common route of administration:
ORAL
- administration is the most common, least expensive, and most convenient route for most clients.
- the drug is swallowed.
- major disadvantages can include an unpleasant taste of the drugs, irritation of the gastric mucosa, irregular absorption from the GI tract, slow absorption, and, in some cases, harm to the client's teeth.
SUBLINGUAL
- a drug is placed under the tongue, where it dissolves. In a relatively short time, the drug is largely absorbed into the blood vessels on the underside of the tongue.
- should not be swallowed.
BUCCAL
- means "pertaining to the cheek."
- a medication (e.g., a tablet) is held in the mouth against the mucous membranes of the cheek until the drug dissolves
Topical applications
are those applied locally to the skin or to the mucous membranes. They affect only the area to which they are applied.
Dermatologic preparations
topical preparations—applied to the skin.
Instillations and irrigations
—applied into body cavities or orifices, such as the urinary bladder, eyes, ears, nose, rectum, or vagina.
Inhalations
administered into the respiratory tract by a nebulizer or positive pressure breathing apparatus. Air, oxygen, and vapor are generally used to carry the drug into the lungs.
is defined as other than through the alimentary or respiratory tract; that is, by needle.
1. Intradermal
2. Subcutaneous
3. Intramuscular
4. Intravenous
common routes for parenteral administration:
Intradermal
- parenteral administration Under the epidermis (into the dermis)
- The main advantage is fast absorption.
Subcutaneous
parenteral administration Into the subcutaneous tissue, just below the skin.
Intramuscular
parenteral administration Into the muscle
Intravenous
parenteral administration Into a vein
1. Intra-arterial
2. Intracardiac
3. Intra-articular
4. Intraosseous
5. Intraspinal/Intrathecal
6. Intrapleural
7. Epidural
Less Commonly used routes for parenteral administration:
Intra-arterial
parenteral administration Directly or into an artery.
Intracardiac
parenteral administration Directly or into the cardiac muscles, your myocardium.
Intra-articular
parenteral administration Directly or into the joints
Intraosseous
parenteral administration into a bone
Intraspinal/Intrathecal
parenteral administration Into the spinal canal
Intrapleural
parenteral administration into the pleural space
Epidural
parenteral administration into the epidural space
1.Prescribing
2. Transcribing
3. Dispensing
4.Administering
Safety Strategies to Prevent Medication Administration Errors:
1. IDENTIFY THE CLIENT
2. INFORM THE CLIENT
3. ADMINISTER THE DRUG
4. PROVIDE ASSISTIVE INTERVENTIONS AS INDICATED
5. RECORD THE DRUG ADMINISTERED
6. EVALUATE THE CLIENT'S RESPONSE TO DRUG
PROCESS OF ADMINISTERING MEDICATIONS:
1. RIGHT CLIENT
2. RIGHT MEDICATION
3. RIGHT DOSE
4. RIGHT TIME
5. RIGHT ROUTE
6. RIGHT EDUCATION
7. RIGHT ASSESSMENT
8. RIGHT DOCUMENTATION
9. RIGHT EVALUATION
10. RIGHT TO REFUSE
THE RIGHTS OF MEDICATION ADMINISTRATION:
take
Rx
before
ā
after
p̄
with
c̅
without
s̄
nothing by mouth
NPO
before meals
a.c.
after meals
p.c.
keep vein open/ to keep open
KVO/TKO
discontinue
D.C./disc.
cubic centimeter
cc
drop/drops
gtt[s]