PNN Top 400

Bumex

Bumetanide

LOOP Diuretic

(C/I: Sulfa)

(Note: 1mg Bumex = 40mg Lasix)

Lasix

Furosemide

LOOP Diuretic

(Note: protect from light)

Torsemide

Demadex

LOOP Diuretic

Thalitone

Chlorthalidone

Thiazide diuretic

Zaroxolyn

Metolazone

Thiazide diuretic

(only thiazide can used in renal failure pt)

Aldactone, CaroSpir

Spironolactone

Potassium-Sparing Diuretic

(SE: gynecomastia)

(Note HF dose = 50mg QD)

Lotensin

“Give me the Low down Ben”

Benazepril

ACE-I

Vasotec

Enalapril

ACE-I

(Only ACE-I that is IV)

Zestril; Prinvil

Lisinopril

ACE-I

Zestoretic

Lisinopril + HCTZ

ACE-I + Thiazide diuretic

Accupril

Quinapril

ACE-I

Altace

Ramipril

ACE-I

(Only ACE-I that comes in CAPsules)

Entresto

Sacubitril/Valsartan

angiotensin receptor-neprilysin inhibitors (ARNi).

(C/I with ACEi if given within 36 hours)

Avapro

Irbesartan

ARB

Cozaar

Losartan

ARB

Diovan

Valsartan

ARB

Diovan HCT

Valsartan with HCTZ

ARB + thiazide diuretic

Benicar

Olmesartan

ARB

Micardis

Telmisartan

ARB

Normodyne
“Norm is in the Lab”

Labetalol

Beta-Blocker

(Take with food. Safe to use in preg)

Bystolic

Nebivolol

BB

(increase nitric oxide) (MOA: Vasodilates)

Tenormin

Atenolol

BB

Coreg, Coreg CR

Carvedilol

BB

(Take with food)

Hyzaar

Losartan + HCTZ

ARB + thiazide diuretic

Maxzide; Dyazide

Hydrochlorothiazide + Triamterene

thiazide + potassium diuretic

Inderal

Propranolol

BB

(Take with food)

Lopressor

Metoprolol tartrate

BB

(IR-Take with food)

Toprol XL

Metoprolol succinate

BB

(can split in half)

(for HF pt = start 12.5mg and increase to 200mg/day)

Zebeta

Bisoprolol

BB

Calan SR, Veralan, Veralan PM

Verapamil

Calcium Channel Blocker

(PO/IV forms only)

(inhibitor of 3A4)

(ventricular rate control)

Cardizem, Tiazac, Taztia XT

Diltiazem

Calcium Channel Blocker

(PO/IV forms only)

(inhibitor of 3A4) (ventricular rate control)

Norvasc

Amlodipine

Calcium Channel Blocker

(sub of CYP3A4, and weak inhib to it too)

Plendil

Felodipine

Calcium Channel Blocker

(ER use only)

(Substrate of CYP3A4) (Do not crush or chew) (QD freq.)

Procardia, Procardia XL

Nifedipine

Calcium Channel Blocker

(Sub of CYP3A4)

Catapres, CatapresTTS, Kapvay

Clonidine

Centrally Acting Alpha-2 Agonist

(1 ptch Q 7 days) (Kapvay is clonidine ER indicated for ADHD)

Tenex, Intuniv

Guanfacine

Centrally Acting Alpha-2 Agonist

(Tenex is indicated for HTN) (Intuniv is indicated for ADHD)

Apresoline

Hydralazine

Vasodilator

(safe in preg) (BiDil (Isosorbide dinitrate + Hydralazine = for HF)

Minipress

Prazosin

Alpha-1 Blocker

(short acting)( not for BPH; only HTN)

Cardura, Cardura XL

Doxazosin

Alpha-1 Blocker

(indicated for HTN and BPH) (Titrated to decrease orthostatic decrease BP)

Hytrin

Terazosin

Alpha-1 Blocker

(indicated for HTN and BPH) (Titrated to decrease orthostatic decrease BP)

Flomax

Tamsulosin

Alpha-1 Blocker

(C/I sulfa) (take 30 min before meals)

Rapaflo

Silodosin

Alpha-1 Blocker

(QD with food) (Caps can be open and sprinkled onto applesauce)

Uroxatral

Alfuzosin

Alpha-1 Blocker

(take with same meal each day)

Avodart

Dutasteride

5-alpha reductase inhibitor

(BPH: Males- Oral 0.5mg QD alone or in combo with tamsulosin)

Proscar, Propecia

Finasteride

5-alpha reductase inhibitor

(Proscar-5mg for BPH/ Propecia-1mg for male pattern baldness)

Lotrel

Amlodipine + Benazepril

CCB + ACE-I

Tarka

Verapamil + Trandolapril (with food)

CCB + ACE-I

Prestalia

Amlodipine + Perindopril

CCB + ACE-I

Exforge

Amlodipine + Valsartan

CCB + ARB

Twynsta

Amlodipine + Telmisartan

CCB + ARB

Azor

Amlodipine + Olmesartan

CCB + ARB

Caduet

Amlodipine + atorvastatin

CCB + Statin

Consensi

Amlodipine + celecoxib

CCB + NSAID (COX-2 Inhib)

Ismo, Imdur

Isosorbide mononitrate

IR- 20mg BID with the 2 dose given 7 hours apart

Isordil

Isosorbide dinitrate

(do not administer around the clock to prevent tolerance to nitrate effect; allow nitrate-free intervals; >/= 14 hours for IR product and >18 hours for SR products)

(IR products is for BID dosing, and TID dosing)

Nitrostat, NitroBid

Nitroglycerin

(“Nitro-GLASS-cerin”; IV must be in GLASS bottle)

Ranexa

Ranolazine

Anti-Anginal

(Indicated for chronic stable angina) (C/I hepatic impairment)

UFH

Heparin

Antithrombin Activator

(IV/SC) IV is for tx; SQ is for PPX

• VTE Prophylaxis: 5000 u SC q8-12 hrs

• VTE tx: Bolus IV 80 units/kg; then 18 units/kg/hr; adjust depending on aPTT; check Q6 hrs.

• Heparin lock flush is intended to maintain "open" IV devices.

• No renal adjustments needed

Lovenox

Enoxaparin

Antithrombin Activator

(Monitor: platelet count, Hgb, Hct, fecal occult blood, signs of bleeding, anti-factor Xa levels, and SCr.) look at notes for dosing

Fragmin

Dalteparin

Antithrombin Activator

PPx: 2500-5000 units SC QD

Contra: Pork Allergy

Can cause ↑K+

Pradaxa

Dabigatran

Direct Thrombin Inhibitor

(MOA: inhibit factor 2a)

(Antidote is Praxbind aka idarucizumab)

(needs to be kept in original bottle and only good for 4 months)

Eliquis

Apixaban

Factor Xa Inhibitor

(dose BID)

(antidote = andexanet alfa (andexxa) which is IV only)

Jantoven, Coumadin

Warfarin

Vitamin K Antagonist

(Monitor INR; Hgb, Hct, signs of bleed)

(Antidote: Vit K (phytonadione or Mephyton)

Plavix

Clopidogrel

Antiplatelet= Thienopyridine P2Y12 platelet receptor Inhibitor

(loading dose 300 then 75mg QD)

Effient

Prasugrel

Antiplatelet= Thienopyridine P2Y12 platelet receptor Inhibitor

(Loading dose of 60mg then 10mg QD)

Brilinta

Ticagrelor

Antiplatelet= Thienopyridine P2Y12 platelet receptor Inhibitor

(Loading dose of 180mg then 90mg BID) (Black box: C/I Aspirin >100mg)

Aggrenox

Dipyridamole + Aspirin

Antiplatelet = Adenosine deaminase Inhibitor + Aspirin

(C/I in patient with salicylate allergy)

Pacerone, Nexterone

Amiodarone

class III antiarrhythmic drug

(DDI with warfarin) (DDI with Sofosbuvir)

Multaq

Dronedarone

class III antiarrhythmic drug

(Take with food; avoid Grapefruit; watch for liver and HF)

Betapace, Betapace AF

sotalol

Beta-Blocker

Tambocor

Flecainide

class I antiarrhythmic

Only comes in PO

Tikosyn

Dofetilide

class III antiarrhythmic

(only comes in PO) (C/I in CrCl <20), C/I pt with HCTZ, citalopram due to QTc

Lanoxin, Digitek, Digox

Digoxin

positive inotrope; Group V antiarrhythmic

(Antidote: DigiFAB)

Lipitor

Atorvastatin

Statin HMG-CoA Reductase Inhib

(Max 80mg)(Combo with amlodipine = Caduet)

Crestor

Rosuvastatin

Statin HMG-CoA Reductase Inhib

(Max 40mg) (Note Asian start at 5mg and max at 20mg)

Zocor

Simvastatin

Statin HMG-CoA Reductase Inhib

(Max 40mg) (Combo with Ezetimibe = Vytorin)

Pravachol

Pravastatin

Statin HMG-CoA Reductase Inhib

(Least drug interaction; Max at 80mg)

Mevacor

Lovastatin

Statin HMG-CoA Reductase Inhib

(IR with evening meals; Max at 80mg)

Lopid

Gemfibrozil

Antilipemic; Fibrate

(do not use with statin due to increase myopathy)

Tricor, Lipofen, Antara, Lofibra

Fenofibrate

Antilipemic; Fibrate

(Lipofen and Antara are to be taken with food)

Trilipix, Fibricor

Fenofibrate Acid

Antilipemic; Fibrate

Praluent

Alirocumab

Antilipemic; PCSK9 Inhib

(SQ once Q 2 wks; in the refrigerator)

Repatha

Evolocumab

Antilipemic; PCSK9 Inhib

(SQ 140mg Q2wks or 420 once monthly; in the refrigerator)

Zetia

Ezetimibe

Antilipemic

(10mg QD)

Vytorin

Ezetimibe + Simvastatin

Antilipemic + Statin

Vitamin B3, Niacor, Niaspan

Niacin

Vitamin B-3; Antilipemic

(with food, ASA 325mg 30 minutes before dose to reduce flushing)

Lovaza

Omega-3

Omega-3 Fatty Acid; Antilipemic

(increase bleeding risk in warfarin)

Synthroid, Levoxyl, Levothyroid

Levothyroxine

Synthetic T4 Thyroid Hormone

(T4; Must take on empty stomach)

Cytomel, Triostat

Liothyronine

Synthetic T3 Thyroid Hormone

(T3; rapid absorption, rapid onset)

PTU

Propylthiouracil

Antithyroid Agent

(Preferred in 1st trimester of pregnancy)

Tapazole

Methimazole

Antithyroid Agent

(preferred in 2nd or 3rd trimester of pregnancy)

Androgel, Androderm

testosterone

Androgen

(comes in gel and transdermal patch, It is a C3 med)

Estrace, Premarin

Estradiol

Estrogen

(Formulation: oral tablet and vaginal cream)

Provera/Depo-Provera

Medroxyprogesterone

Contraception; Progesterin-ONly

(Oral tabs; Depo-Provera-Contraceptive; IM/SQ Q3months)

Prometrium

Progesterone (C/I peanut allergy)

CombiPatch

Estradiol + norethindrone

Estrogen and progestin combination

(1 patch twice weekly; Refrigerate)

Proventil HFA, Ventolin HFA, ProAir HFA, RespiClick

Albuterol

SAB-2A

(Priming: ProAir-3 sprays; Proventil/Ventolin HFA-4 sprays) (Reprime if >14 days)

(RespiClick: Discard after 13 months)

Xopenex

Levalbuterol

SAB-2A

(Neb: once foil is open, good for 2 weeks out of foil, 1 week) (HFA prime 4 sprays and after 3 days of non-use)

Asmanex

Mometasone

Corticosteroid

(Discard 45 days after removal from pouch)

Flovent HFA, Flovent Diskus, Arnuity Ellipta

Fluticasone

Corticosteroid

(All Ellipta formulation are QD)