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what is a replicon?
entity that is replicating
What is the semiconservative nature of DNA?
During this process, each new DNA molecule contains one original (parental) strand and one newly synthesized (daughter) strand
continue from #1: what does this mean?
the information from ½ of the original DNA molecule is conserved in each daughter strand.
What are the different types of DNA replication in prokaryotes?
theta replication and rolling-circle replication
What are the different types of DNA replication in eukaryotes?
linear DNA replication
theta replication summary
double stranded DNA unwinds at origin of replication (bidirectionally), forms a replication bubble and synthesizes around the circle, eventually making another DNA molecule
what keeps the 2 DNA molecules apart when replicating in prokaryotes?
structural maintenance of chromosomes (SMC in chapter 2 mentioned)
what is the outcome of theta replication?
2 circular DNA molecules
Rolling-circle replication summary
replication starts at 3’ end of broken dna strand, using the INNER circle as a template as the 5’ end from the outside circle unravels. this is unidirectional; when 5’ outside strand is cleaved off, it can become a template for synthesis of a complementary strand
Rolling-circle outcome?
multiple circular DNA molecules