PLASMA CELL

PLASMA CELL

Fully differentiated B Lymphocyte

B Lymphocyte

PLASMA CELL is Fully differentiated ____

PLASMA CELL

Not normally found in the circulating blood but are seen in the bone marrow in concentrations that do not normally exceed 2%.

bone marrow

Plasma Cell are found in the?

2%

Plasma Cell are not normally found in the circulating blood but are seen in the bone marrow in concentrations that do not normally exceed __%

Plasma cells

Arise as the end stage of B-cell differentiation after antigenic stimulation

Plasma cells

Responsible for producing specific immunoglobulins or antibodies directed towards the particular antigen

immunoglobulins, antibodies

Plasma Cells responsible for producing specific ________ or _________directed towards the particular antigen

14 to 20 μm

PLASMA CELL: Overall size

hof

Cytoplasm is abundant, dark blue with a visible lighter staining area around the nucleus, called the

Golgi apparatus

Cytoplasm is abundant, dark blue with a visible lighter staining area around the nucleus, called the hof, which represents the area occupied by the

active production, secretion

The distinctive dark blue cytoplasm indicates ______ and ______ of proteins, mainly antibodies.

Russell bodies

Cytoplasmic inclusions can include _____ _____ (small globules within the cytoplasm) which are acidophilic, refractile globules that represent gamma globulin (protein) secretions