Radbio - Unit 10 & 11

ARS

acute radiation syndrome

time frame of ARS

short time frame of less than 6 months

hematologic syndrome

bone marrow/hematopoietic syndrome

• occurs over 1 Gy

gastrointestinal syndrome

removal of GI lining = leads to dehydration

• occurs over 10 Gy

central nervous sydnrome

combination of gastrointestinal syndrome & hematologic syndrome

• occurs over 50 Gy

stages of ARS

1. prodromal - NVD: occurs over .5 Gy

2. Latent

3. Manifest

4. recovery or death

LD 50/30 dose

3-6

erythema

red skin

epilation

hair loss

desquamination

scaling

radiodermatitis

roentgen ray burns

what dose causes temporary sterility and permanent sterility

temporary: 2.5

permanent: 5.0

stochastic

• random, like a lottery. one person might get it, another person might not

• nonthreshold, linear curves

• ex. cancer, leukemia, genetic effects

deterministic

tissue reaction

• happens to everyone

epidemiology

study of distribution and causes of diseases in human populations

what chronic disease did radium dial painters receive

bone cancer

what chronic disease did uranium miners receive

lunch cancer

what is cataract genesis

radiation to the radiosensitive lens