Lecture on Leptospirosis and Lyme Disease

This set of flashcards covers key concepts from the lecture on leptospirosis and Lyme disease, including diagnosis, treatment, symptoms, and management.

What is the typical treatment duration for leptospirosis?

Four to six weeks, often consisting of two weeks of ampicillin and two weeks of doxycycline.

Which symptoms are associated with Lyme disease?

Fever, polyarthropathy, and glomerulonephritis.

How is Lyme disease transmitted?

Through the Ixodes tick.

What is the role of the OspA protein in Borrelia burgdorferi?

It is important for adhesion in the gut of the tick.

What does a positive antibody titer indicate?

Exposure to the pathogen, not necessarily active infection.

What are common hematological findings in dogs with Lyme disease?

Leukocytosis, leukopenia, thrombocytopenia, and anemia may be present.

How is a diagnosis of Lyme disease typically confirmed?

Through a C6 antibody test, as culture is difficult.

What indicates a poor prognosis in dogs with Lyme disease?

The presence of protein losing nephropathy.

What is the recommended antibiotic for treating Lyme disease?

Doxycycline.

What is the significance of checking urine protein-creatinine ratios in Lyme positive dogs?

It helps to assess for protein losing nephropathy.

How should asymptomatic non-proteinuric Lyme positive dogs be managed?

They should be monitored regularly, typically every six months.

What is the function of antithrombin III and its relevance in Lyme disease?

It controls blood clotting; its loss increases the risk of thromboembolism.

Which protein helps Borrelia evade the host’s immune response?

OspC protein.

What are potential complications of Lyme disease?

Relapses, chronic kidney disease, hypertension, and thromboembolism.

How often should symptomatic Lyme disease dogs be monitored using the C6 test?

Regularly to assess the effectiveness of treatment.

What might happen if a vaccinated dog gets Lyme disease?

Vaccination does not apply if the dog is infected; it should not be vaccinated.

What factors can influence the decision to treat an asymptomatic Lyme positive dog?

The presence of symptoms and proteinuria results.

What should be considered for tick prevention?

Good tick control is essential as it can prevent transmission.