Antipsychotics in Mental Health Nursing

Comprehensive vocabulary flashcards covering common antipsychotic medications, their dosages, depot preparations, and side effects as detailed in the lecture transcript.

Olanzapine

An antipsychotic used for schizophrenia, psychosis, and mania in bipolar disorder, with common oral doses of $5–20\,mg/day$ (typically starting at $10\,mg$) and common effects including sedation, weight gain, and raised glucose/lipids.

Zypadhera

The depot preparation of Olanzapine ($210\,mg$, $300\,mg$, or $405\,mg$) which carries a specific risk of post-injection delirium/sedation syndrome and requires at least $3\text{ hours}$ of observation after injection.

Risperidone

Used for schizophrenia/psychosis and manic episodes with an oral dose of $2–6\,mg/day$; it may cause EPS, akathisia, raised prolactin, or rare effects like priapism and QT prolongation.

Risperdal Consta and Okedi

Depot forms of Risperidone; Risperdal Consta is given in doses of $25\,mg$, $37.5\,mg$, or $50\,mg$ every $2\text{ weeks}$, while Okedi is given as $75/100\,mg$ every $28\text{ days}$.

Aripiprazole

An antipsychotic for schizophrenia and mania in bipolar I disorder, with common oral doses of $10–30\,mg/day$; notable for risks of impulse-control disorders such as gambling, compulsive spending, or hypersexuality.

Quetiapine

Medication for schizophrenia ($150–750\,mg/day$), bipolar mania ($200–800\,mg$), and bipolar depression ($300\,mg$); common effects include orthostatic hypotension, dizziness, and dry mouth.

Clozapine

A treatment-resistant schizophrenia medication requiring mandatory blood monitoring; starting at $12.5\,mg$ with a specialist maximum of $900\,mg/day$. Dangerous effects include agranulocytosis, myocarditis, and severe constipation/ileus.

Haloperidol

Used for psychosis, acute agitation, and mania with a maximum oral dose of $20\,mg/day$; notably associated with EPS, acute dystonia, and QT prolongation/Torsades.

Haloperidol decanoate

The depot preparation of Haloperidol available in strengths of $50\,mg/mL$ or $100\,mg/mL$.

Zuclopenthixol (Clopixol)

Antipsychotic for schizophrenia with a depot dose of $200–500\,mg$ every $1–4\text{ weeks}$; important risks include NMS, QT prolongation, arrhythmias, and VTE.

Paliperidone

Used for schizophrenia/schizoaffective illness with oral doses of $3–12\,mg/day$; common side effects include prolactin increase, weight gain, and sedation.

Xeplion and Trevicta

Depot preparations of Paliperidone; Xeplion is administered monthly, and Trevicta is administered every $3\text{ months}$ after stabilization.

Neuroleptic Malignant Syndrome (NMS)

An important and potentially dangerous effect listed for all major antipsychotics mentioned including Olanzapine, Risperidone, Aripiprazole, Quetiapine, Haloperidol, Zuclopenthixol, and Paliperidone.

Extrapyramidal Side Effects (EPS)

Side effects characterized by movement disorders, specifically noted as common for Risperidone, Haloperidol, Zuclopenthixol, and Paliperidone.