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Sound
Vibrations of air that our ears detect as hearing
Compressed air
Air molecules pushed closely together; higher density
Rarefied air
Negative pressure; lower density
Hertz
How sound is measured; cycles per second
Intensity (amplitude)
Frequency (pitch)
Complexity (timbre)
Intensity (Amplitude)
High the wave = loud sound // lower wave = soft sound
Frequency (Pitch)
Waves far apart = low pitch // waves close together = high pitch
Complexity (Timbre)
Pure tone vs tones layered on top of one another
ex) One section of an orchestra playing vs the whole orchestra
Outer Ear
The part of the ear you can actually see
Pinna: Cartilage that acts as a funnel; Grabs sound waves and funnels them down the auditory canal
Auditory canal: Channel that directs sound waves to the eardrum
Middle Ear
Ear drum (tympanic membrane): Vibrates when struck by sound waves, converting air pressure changes into mechanical movement for the ossicles
Ossicles: 3 bones in the middle ear that are hinged together
Inner ear
Cochlea: 3 fluid filled canals
cochlea —> brain; exam mention
Transduction
Going from one modality to another; takes place in cochlea (inner ear)
Sound waves —> electrical chemical signals
How sound travels
Pinna → auditory canal → Tympanic membrane (ear drum): flexible, as it is hit with compressed air it will flex and move → ossicles: as the eardrum moves the bone will shift to amplify the signal so it can be detected by the brain → Oval window (on the cochlea): where the ossicles contact the cochlea by banging against it rhythmically → cochlea, filled with fluid, fluid is moved
Ear infection
Bacteria growing inside of the fluid in the middle ear
Swelling; push on ear drum and irritate ear
Treatment for chronic infections = putting tube through ear drum to open it up
Middle Ear Fluid
Fluid exchanges everyday; typically clear
Eustachian tube: Allows middle ear fluid to drain regularly
During ear infections, the tube can narrow allowing the fluid to sit rather than drain
Cochlear duct
Middle chamber of the cochlea containing endolymph and the organ of Corti (where hearing transduction occurs)
Endolymph: The fluid inside of the cochlear duct; mostly potassium (K+)
Organ of corti: 2 membranes in your hair cells where transduction happens inside of the cochlear duct; runs the whole length of cochlea curl
Basilar membrane
Membrane in the cochlea that moves in response to fluid waves; movement bends hair cells to trigger electrical signals
Tectorial Membrane: Structure above hair cells; movement of the basilar membrane causes hair cells to press against it, bending the cilia
Transduction
Converting mechanical energy from sound vibrations into neural (electrical) signals by hair cells
Perilymph (tympanic and vestibular canals)
Fluid in the tympanic and vestibular canals that carries sound-induced waves through the cochlea
Mechanically gated ion channels
Opens when hair cell cilia bend, allowing ions to enter and generate receptor potentials
Tiplink
Pulls the lid open on these ion channels → diffusion and electrostatic pressure push ions inside (depolarize)
Depolarization (more positive): Bending towards the tall tiplink = ion channel open
Hyperpolarization (more negative): Bending towards the short tiplink = ion channel close
Cilia
Hair cells on the basilar membrane
Inner: Mediate transduction; less common
Losing all of these would make a person deaf
Outer: Amplify the signal of the inner cilia; more common
Can have less but still have sound
Place Coding
definition
Base: Needs stronger waves (high frequency) to move the base because it's narrow
When this is activated ur brain knows it's a high pitch/frequency sound
Apex: Easier to move, wide, flexible
When this is activated, your brain knows it's a low pitch/frequency sound
Temporal Lobe
Brain region that receives and interprets auditory information like pitch and volume
Auditory cortex: Part of the temporal lobe responsible for processing and identifying sounds
Superior Olivary Nucleus (hind brain/brainstem)
Brainstem structure that compares input from both ears to determine sound location; Can help up respond to sounds before we hear it
Input from right and left side of ear
Medial geniculate Nucleus
Subsection of the thalamus (diencephalon) that sends auditory information to the auditory cortex
Conduction Deafness
Sound waves aren't hitting the ear drum OR aren’t being relayed to the cochlea; involves an issue with the middle or outer ear; usually temporary
Sensorineural Deafness
An issue in your cochlea; Hair cilia are dying off or didnt form/ didn’t form properly; most common/born deaf
Central Deafness
Damage to auditory structures in the brain (auditory cortex/temporal lobe); very rare
Fiber Types (skin)
Aa (Alpha): Fastest because of myelination and bigger diameter
Ab (Beta): Mechanorecepters use the Aa beta fibers
Aδ (delta): Used for pain/temp/itching
C: Used for pain/temp/itching
Adaptation (skin)
Rapid: Sensory stimulus adapts quickly; mark the start and stop of a stimulus
Slow: Start firing when the stimulus is presented and maintain/continue it; isnt as instant
Stimulus Strength (skin)
definition/ AP frequency?
ex) As you get pressure applied to the skin, onion like shaped thing pulls and deforms it (based on strength of vibration/pressure)
Receptive Field
The point where sensory info is picked up
Smaller receptive fields in smaller areas (like fingers); higher number of sensory neurons in these places
Density: High receptor density = smaller receptive fields and greater sensitivity (e.g., fingertips).
Two point discrimination
Putting 2 pencils on someones arm; “how many things are touching your skin?”
If the 2 pencils are in the same receptive field, theyll say one thing but if they are in different receptive field theyll say 2 things
Receptive field size varies
Dorsal Column System (Ascension sensory)
Ascending spinal pathway that carries sensory info to the thalamus → primary somatosensory cortex in the parietal lobe
Nocireceptors
Pick up painful stimuli; free nerve endings
Multiple types of pain receptors
chemical signal → nocireceptor → Signal sent through dorsal root ganglia → into dorsal column of spinal cord
Types of nocireceptors
Mechanical: Respond to intense pressure, cuts, or tissue damage
Chemical: Respond to irritating chemicals or inflammation
Thermal: Respond to extreme heat or cold
Fiber nocireceptor types
Aδ: Pain/temp; initial pain response
C: Pain/temp/itch; secondary pain response throbbing or lingering pain/irritation
Antrolateral (spinothalamic) system
Ascending pain pathways
Fibers are taken in through dorsal root ganglia and cross over immediately and ascend on the right side (contralateral side)
Spinal cord → medulla → pons → Midbrain → forebrain
Messy signal because it hits multiple levels
Decussation
Crossing of neural fibers from one side of the body to the opposite side of the brain
Touch: Decussation happens in Hindbrain and medulla
Pain: That decussation or crossing to contralateral side is happening at the Spinal cord
Psychological control of pain
Study done measuring pain using voltage shocks. They tell participants they have 2 drugs (cheap vs expensive) when in reality they were both placebo. People taking the more expensive sugar pill was more effective compared to the cheaper pill, people said wasn't as effective
Analgesic
A drug that is supposed to reduce pain
Aspirin, morphine
5 basic tastes
Salty
Sour
Sweet
Bitter
Umami (msg, smelly cheeses, meatiness)
Flavor
Taste (20%) combined with smell (80%)
Taste buds
Found in trenches/grooves of tongue
10-14 a say
peripheral nervous system
Gustatory pathway
Sense of taste; ipsilateral (stays on the same side)
Insular cortex: Where sensory info from taste is processed; ticked inside lateral sulcus
Hits the thalamus before it goes to it's primary cortical region; true for most
Taste cells (Gustatory cells)
Receptor cells in taste buds that detect one type of taste (sweet, sour, salty, bitter, umami)
Gustatory (afferent) axons: Carry taste information from taste buds to the brain
Cranial Nerves
Takes taste information to the brain
Glossopharyngeal (IX): Carries taste from the posterior third of the tongue.
Facial nerve (VII): Carries taste from the front two-thirds of the tongue.
Vagus nerve (X): Carries taste and sensory input from the epiglottis and throat.