IPS1 - [Modified Release Dosage Forms] - Non-Oral Modified Release Systems

● Ocular inserts

● Parenteral systems

● Vaginal inserts

● Subdermal implants

NON-ORAL modified release systems include:

● Ocusert

● Lacrisert

Examples of OCULAR inserts

Ocusert

[OCULAR INSERTS]

This is an ocular PILOCARPINE therapeutic system designed to release medication gradually over a 7-day period, used in the treatment of GLAUCOMA.

Pilocarpine

[OCULAR INSERTS]

OCUSERT is an ocular therapeutic system containing _____ designed to release medication gradually over a 7-day period, used in the treatment of GLAUCOMA.

7-day period

[OCULAR INSERTS]

OCUSERT is an ocular PILOCARPINE therapeutic system designed to release medication gradually over a ___-day period, used in the treatment of GLAUCOMA.

Glaucoma

[OCULAR INSERTS]

OCUSERT is used in the treatment of ____

Lacrisert

[OCULAR INSERTS]

A small, sterile insert used for the treatment of DRY EYES.

Dry eyes

[OCULAR INSERTS]

LACRISERT is a small, sterile insert used for the treatment of ___

● Depo-Provera

● Depot Vitamin B12

● Penadur LA

Examples of PARENTERAL SYSTEMS include:

Depo-Provera

[PARENTERAL SYSTEMS]

A CONTRACEPTIVE injection that provides sustained release of MEDROXYPROGESTERONE ACETATE for long-term pregnancy prevention.

Medroxyprogesterone acetate

[PARENTERAL SYSTEMS]

Depo-Provera is a CONTRACEPTIVE injection that provides sustained release of ____for long-term pregnancy prevention (3 months).

3 months

[PARENTERAL SYSTEMS]

Depo-Provera is used as a contraception for up to ___ months.

Depot Vitamin B12

[PARENTERAL SYSTEMS]

This is an injectable formulation of vitamin B12 (HYDROXOCOBALAMIN) for patients with ANEMIA for up to 3 months.

Anemia

[PARENTERAL SYSTEMS]

Depot Vitamin B12 is an injectable formulation of vitamin B12 (HYDROXOCOBALAMIN) for patients with ___ for up to 3 months.

3 months

[PARENTERAL SYSTEMS]

Depot Vitamin B12 is an injectable formulation of vitamin B12 (HYDROXOCOBALAMIN) for patients with ANEMIA for up to ___ months.

Penadur LA

[PARENTERAL SYSTEMS]

A LONG-ACTING injectable PENICILLIN-BENZATHINE preparation for BACTERIAL INFECTION.

Penicillin-benzathine

[PARENTERAL SYSTEMS]

Penadur LA containes _____ preparation for BACTERIAL INFECTION.

Bacterial infection

[PARENTERAL SYSTEMS]

Penadur LA is used for ____

● Cervidil vaginal insert

● Crinone gel

● Estring

Examples of VAGINAL INSERTS include:

Cervidil Vaginal Insert

[VAGINAL INSERTS]

This contains DINOPROSTONE and is used for the INDUCTION OF LABOR by gradually releasing prostaglandins to ripen the cervix.

Dinoprostone

[VAGINAL INSERTS]

Cervidil Vaginal Insert contains ___ and is used for the INDUCTION OF LABOR by gradually releasing prostaglandins to ripen the cervix.

Induction of labor

[VAGINAL INSERTS]

Cervidil Vaginal Insert is used for ____

Crinone Gel

[VAGINAL INSERTS]

A PROGESTERONE-containing vaginal gel used to assist REPRODUCTION.

Progesterone

[VAGINAL INSERTS]

Crinone Gel contains _____ used to support reproduction.

Assist reproduction

[VAGINAL INSERTS]

Crinone Gel is used to ____

Estring

[VAGINAL INSERTS]

A flexible VAGINAL RING that delivers ESTRADIOL locally to treat urogenital symptoms associated with postmenopausal atrophy of the vagina.

Estradiol

[VAGINAL INSERTS]

Estring is a flexible VAGINAL RING that delivers ____locally to treat urogenital symptoms associated with postmenopausal atrophy of the vagina.

urogenital symptoms associated with postmenopausal atrophy of the vagina

[VAGINAL INSERTS]

Estring is a flexible VAGINAL RING that delivers ESTRADIOL locally to treat _____

Subdermal Implants

These are solid dosage forms inserted beneath the skin either using specialized injectors or surgical incisions.

● Special injectors

● Surgical incisions

Subdermal Implants are designed to be inserted under the skin with the use of ____ or by _____

● Zoladex implant (Zeneca)

● Norplant system (Wyeth-Ayerst)

Examples of SUBDERMAL IMPLANTS include:

Zoladex Implant (Zeneca)

[SUBDERMAL IMPLANTS]

This contains GOSERELIN ACETATE used for the treatment of ADVANCED PROSTATIC CANCER.

Goserelin acetate

[SUBDERMAL IMPLANTS]

Zoladex Implant (Zeneca) contains ____ used for the treatment of ADVANCED PROSTATIC CANCER.

Advanced prostatic cancer

[SUBDERMAL IMPLANTS]

Zoladex Implant (Zeneca) contains GOSERELIN ACETATE used for the treatment of ____.

Zeneca

[SUBDERMAL IMPLANTS]

Manufacturer of ZOLADEX Implant

Norplant System (Wyeth-Ayerst)

[SUBDERMAL IMPLANTS]

This contains LEVONORGESTREL that provides up to 5 years of CONTRACEPTION.

Levonorgestrel

[SUBDERMAL IMPLANTS]

Norplant System (Wyeth-Ayerst) contains ____ that provides up to 5 years of CONTRACEPTION.

5 years

[SUBDERMAL IMPLANTS]

Norplant System (Wyeth-Ayerst) contains LEVONORGESTREL that provides up to ___ years of CONTRACEPTION.

contraception

[SUBDERMAL IMPLANTS]

Norplant System (Wyeth-Ayerst) contains LEVONORGESTREL that provides up to 5 years of ____.

Wyeth-Ayerst

[SUBDERMAL IMPLANTS]

Manufacturer of Norplant System