CANCER - tumorgenesis

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4 Terms

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Senescence

Senescence = cell in non-growing state, but viable

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crisis

Crisis = apoptotic death of cells
• Erosion of telomeres leads to chromosomal fusions, karyotype chaos and
cell death
• Cancer cells escape crisis by finding ways to regenerate their telomeres ---
this leads to immortalization, prerequisite for the development of cancers

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c

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c