Four types of hypersensitivity

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4 Terms

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What characterizes Type I hypersensitivity?

Recognition of allergens by IgE on granulocytes, leading to degranulation and inflammation.

2
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What characterizes Type II hypersensitivity?

Recognition of cell-surface molecules and targeting of cells via complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC).

3
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What characterizes Type III hypersensitivity?

IgG or IgM antibodies recognize soluble antigens and form immune complexes that trigger inflammation.

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What characterizes Type IV hypersensitivity?

Activation of T cells by an innocuous antigen, leading to IFN-Îł release and macrophage activation.