L8 - Immunity to Infection

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9 Terms

1
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CD4+ T-cells activate the immune system by…

  • Helping B cells to produce antibodies

  • Provide help to CD8+ Cells

  • Help activate macrophages

2
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When can dendritic cells activate CD8+ T cells directly?

When there is high B7 expression

3
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What type of Ig is made due to IFN-γ

IgG

4
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What type of Ig is made due to IL-4

IgE

5
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What co-stimulatory molecules are required to activate CD4+ T-Cells

CD80/86 on APC and CD28 on CD4+ Cell

6
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What co-stimulatory molecules are required for CD4+ T-Cells and B-Cells

CD40L on CD4+ and CD40 on B Cell

7
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What type of cytokine is made when TH Cell binds to a macrophage

IFN-γ

8
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What change is induced when a CD4+ T-Cell binds to a macrophage

Macrophage is activated and cytokine are released

9
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What change is induced when a CD4+ T-Cell binds to a B-Cell

Creates plasma cells and antibodies