1) Histology of the Kidney and Glomerular Disease

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14 Terms

1
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In the lower third of the ureter, an additional muscle layer is present. What is the orientation of this layer?

Longitudinal

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Which of the following correctly lists the four main histological layers of the urinary bladder wall, from innermost to outermost?

Mucosa, submucosa, muscularis (detrusor muscle), adventitia/serosa

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Which of the following correctly identifies the three main layers of the glomerular filtration barrier (GFB), from innermost to outermost?

Fenestrated endothelium, glomerular basement membrane, podocyte foot processes

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GFR = Kf × [(PGC − PBC) − (πGC − πBC)]

GFR = Kf × [(PGC − PBC) − (πGC − πBC)]

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Which type of glomerular disease is characterized by increased cellularity within the glomeruli, often due to infiltration by inflammatory cells or proliferation of intrinsic cells?

Proliferative

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Which classification of glomerular disease involves expansion and proliferation of mesangial cells and matrix without significant capillary wall involvement?

Mesangial

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Which glomerular disease is characterized by thickening of the glomerular basement membrane due to subepithelial immune complex deposition, typically without significant hypercellularity?

Membranous

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Which type of glomerular disease shows both basement membrane thickening and increased cellularity, with a "tram-track" appearance on light microscopy?

Membranoproliferative

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Which glomerular disease classification is associated with inflammation of small blood vessels and is often seen in ANCA-associated conditions or systemic autoimmune disorders like lupus?

Vasculitis-related

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