GI Enzymes

Where is salivary α-amylase found?

Mouth

What does salivary α-amylase break down?

Starches (carbohydrates)

Where is pepsin active?

Stomach (in the presence of hydrochloric acid)

What does pepsin break down?

Proteins into smaller polypeptides

Where are pancreatic proteases (trypsin, chymotrypsin, carboxypeptidase) active?

Small intestine

What do pancreatic proteases break down?

Proteins and polypeptides

Where are brush-border peptidases (aminopeptidases and dipeptidases) found?

Small intestine

What do brush-border peptidases break down?

Peptides into amino acids

Where is pancreatic lipase active?

Small intestine

What does pancreatic lipase break down?

Emulsified fats (triglycerides)

Where are brush-border enzymes (lactase, maltase, sucrase) found?

Small intestine

What do brush-border enzymes (lactase, maltase, sucrase) break down?

Disaccharides into monosaccharides