Key Features of the Major Acute Myeloid Leukemias (AML)

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Last updated 2:56 PM on 6/24/26
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11 Terms

1
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≥20% blasts, ≥10% maturing granulocytes, Auer rods, dysplasia

AML with t(8;21)

2
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Blasts with both monocytic & neutrophilic differentiation, increased eosinophils/immature eosinophils

AML with inv (16)

3
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Promyelocytes with azurophilic granules, Auer rods

APL with t(15;17)

4
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Monoblasts and promonocytes predominate

AML with t(9;11)

5
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Multilineage dysplasia, RS, increased basophils

AML, therapy related

6
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Any morphology may be seen but myelomonocytic is most common

AML with t(6;9)

7
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Any morphology may be seen except APL

AML with inv(3) or t(3;3)

8
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Megakaryoblastic morphology with small and large megakaryocytes

AML with t(1;22)

9
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Any

AML with FLT3 mutation/ duplication

10
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Myelomonocytic and monocytic features

AML with NPM1 mutation

11
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Variable, generally similar to less differentiated AMLs in FAB scheme (M1, 2)

AML with CEBPA mutation