Pregnancy & Lactation

Metamucil

Psyllium

Indication for Psyllium

constipation

Pharmacologic Category for Psyllium

Fiber supplement

ROA for Psyllium

PO

frequency dose for Psyllium

daily

Citrucel

Methylcellulose

Indication of Methylcellulose

Constipation

Pharmacologic of Category Methylcellulose

Fiber supplement

ROA for Methylcellulose

PO

Frequency Dose Methylcellulose

Daily

FiberCon

polycarbophil

Colace

Docusate Sodium

Indication for Docusate Sodium

Constipation

Pharmacologic category Docusate Sodium

Stool Softener

ROA Docusate Sodium

PO

Frequency for Docusate Sodium

daily

Miralax

-polyethylene glycol

-Lactulose

-Sorbitol

-Magnesium/Sodium salts

Indication for polyethylene glycol

Lactulose

Sorbitol

Magnesium/Sodium salts

Constipation

Pharmacologic Category for polyethylene glycol

Lactulose

Sorbitol

Magnesium/Sodium salts

Osmotic laxatives

ROA for polyethylene glycol

Lactulose

Sorbitol

Magnesium/Sodium salts

PO

Frequency Dose for polyethylene glycol

Lactulose

Sorbitol

Magnesium/Sodium salts

Daily

Ex-Lax

Senna

Indication for Senna

Constipation

Pharmacologic Category for Senna

Stimulant Laxatives

ROA for Senna

PO

Frequency Dose for Senna

Daily

Preparation H, Anusol HC

-Benzocaine

-Lidocaine

-Pramoxine

Tucks

Witch Hazel

Indication of for Benzocaine

Lidocaine

Pramoxine

Hemorrhoids

Pharmacologic Category for Benzocaine

Lidocaine

Pramoxine

Local anesthetic

ROA for Benzocaine

Lidocaine

Pramoxine

Rectally

dose Frequency for Benzocaine

Lidocaine

Pramoxine

Up to 3-6 times daily depending on agent

Indication for Witch hazel

Hemorrhoids

Pharmacologic Category for Witch Hazel

Astringent

ROA for Witch Hazel

Rectally

dose frequency for Witch Hazel

up to 6 times daily

Hydrocortisone

Hydrocortisone

Indication for Hydrocortisone

Hemorrhoids

Pharmacologic category for Hydrocortisone

Steroid

ROA for Hydrocortisone

Rectally

Frequency Dose for Hydrocortisone

Daily

TUMS

calcium carbonate

indication for Calcium Carbonate

GERD/Heartburn

Pharmacologic Category Calcium Carbonate

Antiacid

ROA Calcium Carbonate

PO

Frequency dose Calcium Carbonate

PRN

Tagamet

Cimetidine

Indication for Cimetidine

GERD/Heartburn

Pharmacologic category of Cimetidine

H2RA

ROA for Cimetidine

PO

Frequency Dose for Cimetidine

BID

Pepcid

Famotidine

Indication for famotidine

GERD / Heartburn

Pharmacologic Category for famotidine

H2RA

ROA for Famotidine

PO

Frequency Dose for Famotidine

BID

Prilosec OTC

Omeprazole

Indication for Omeprazole

GERD/Heartburn

Pharmacologic Category for Omeprazole

PPI

ROA for Omeprazole

PO

Frequency Dose for Omeprazole

Daily

Nexium

Esomeprazole

Indication for Esomeprazole

GERD/Heartburn

Pharmacologic Category for Esomeprazole

PPI

roa for Esomeprazole

PO

Frequency dose for Esomeprazole

daily

Prevacid

Pantoprazole

Indication for Pantoprazole

GERD/Heartburn

Pharmacologic Category for Pantoprazole

PPI

ROA for Pantoprazole

PO

Frequency Dose for Pantoprazole

Daily

Zofran

Ondansetron

indication for Ondansetron

Nausea and Vomiting of Pregnancy (NVP

Pharmacologic Category for Ondansetron

Antiemetic

ROA for Ondansetron

PO

Frequency Dose for Ondansetron

Daily to BID PRN

Reglan

Metoclopramide

Indication for Metoclopramide

nausea and vomiting of (NVP)

Pharmacologic Category for Metoclopramide

Antiemetic

ROA for Metoclopramide

PO

Frequency for Metoclopramide

Every 6-8 hours

Glucophage, Fortamet

Metformin

Indication for Metformin

Gestational Diabetes (GDM)

Pharmacologic category for Metformin

Biguanide

ROA for Metformin

PO

Frequency for Metformin

Daily or BID

Glynase, Diabeta

Glyburide

Indication for Glyburide

Gestational Diabetes (GDM)

Pharmacologic Category for Glyburide

Sulfonylurea

ROA for Glyburide

PO

Dose Frequency for Glyburide

Daily or BID

Ecotrin, Bufferin

Aspirin

Indication for Aspirin

Prevention of preeclampsia

Pharmacologic Category for Aspirin

NSAID

ROA for Aspirin

PO

Frequency Dose for Aspirin

daily

Absorption for Pharmacokinetics for Pregnancy

-↓ GI motility

-↓ gastric acidity

-↑ vomiting

Distribution for Pharmacokinetics for Pregnancy

-↑ plasma volume / total body water (TBW)

-↑ body fat

-↓ albumin concentration (via dilution)

Metabolism for Pharmacokinetics for Pregnancy

Estrogen & progesterone can stimulate OR inhibit various CYP450 enzymes

Elimination for Pharmacokinetics for Pregnancy

-↑ GFR/renal blood flow >↑ renal excretion

↑ CO > ↑ drug distribution / elimination