osteoclasts
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When calcium-sensing membrane receptors in the parathyroid gland detect that there are low levels of calcium in the blood, it releases parathyroid hormone. Parathyroid hormone increases the number and activity of **osteoclasts** (*osteo-* means “bone” and *clast* means “broken”), which are cells that break down the tissue in bones and release the minerals, resulting in a transfer of calcium from bone tissue to the blood (this process is called bone resorption).