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Integumentary System
A body system mainly responsible for protection; consists of the skin, hair, glands, and nails.
Integument
Covering.
Main structures of the integumentary system
Skin and accessory structures such as hair, glands, and nails.
Protection
The skin protects against abrasion and ultraviolet light.
Sensation
Sensory receptors in the integumentary system detect heat, cold, touch, pressure, and pain.
Vitamin D production
Exposure to ultraviolet light allows the skin to produce a molecule that can be transformed into vitamin D.
Function of Vitamin D
Helps with calcium absorption.
Temperature regulation
Blood flow beneath the skin and sweat gland activity help regulate body temperature.
Secretion
Release of oil through the skin.
Excretion
Small amounts of waste, excess water, and excess salt are lost through the skin and sweat glands.
Skin
Made up of two major tissue layers: epidermis and dermis.
Two major layers of the skin
Epidermis and dermis.
Subcutaneous tissue
Connective tissue beneath the skin; it is not considered part of the skin.
Epidermis
The most superficial layer of skin; avascular and rests on the dermis.
Avascular
Without blood vessels.
Epidermis tissue type
Keratinized stratified squamous epithelium.
Functions of the epidermis
Prevents water loss and resists abrasion.
Keratin
Protein that makes the skin firm.
Strata
Distinct layers that compose the epidermis.
Five epidermal strata
Stratum corneum, lucidum, granulosum, spinosum, and basale.
Stratum corneum
Most superficial epidermal layer; has 25 or more layers of dead squamous cells.
Function of keratin in stratum corneum
Gives the stratum corneum structural strength.
Dandruff
Excessive sloughing of stratum corneum cells on the scalp.
Callus
Increase in the layers of the stratum corneum caused by friction.
Corn
Thickened stratum corneum over a bony prominence.
Stratum lucidum
3–5 layers of transparent dead cells found in thick skin.
Location of stratum lucidum
Palms of the hands and soles of the feet.
Stratum granulosum
2–5 layers of flattened, diamond-shaped cells.
Stratum spinosum
8–10 layers of many-sided cells with a spiny appearance.
Stratum basale
Deepest or basement layer of the epidermis where mitosis occurs.
Where does mitosis occur in the epidermis?
Stratum basale.
Where are melanocytes located?
Stratum basale.
Dermis
Vascular layer composed of dense collagenous connective tissue.
Cells found in the dermis
Fibroblasts, adipocytes, and macrophages.
Structures extending into the dermis
Nerves, hair follicles, smooth muscles, glands, and lymphatic vessels.
Collagen fibers in the dermis
Help keep the skin intact and provide structural strength.
Elastic fibers in the dermis
Provide resistance to stretching.
Cleavage lines (tension lines)
Directions within the dermis that are more resistant to stretching.
Why are surgical incisions made parallel to cleavage lines?
They tend to gap less, produce less scar tissue, and heal faster.
Dermal papillae
Projections of the upper dermis toward the epidermis that contain many blood vessels.
Dermal papillae and fingerprints
Dermal papillae contribute to the ridges that produce fingerprints and footprints.
Stretch marks
Can occur when overstretching damages the dermis.
Factors determining skin color
Pigments in the skin, blood circulating through the skin, and thickness of the stratum corneum.
Effect of UV light on melanocytes
Stimulates melanocytes to increase melanin production.
Melanin
Group of pigments mainly responsible for skin, hair, and eye color.
Melanocytes
Cells that produce melanin.
Function of melanin
Provides protection against UV light.
Melanosomes
Vesicles into which melanin is packaged.
Carotene
Lipid-soluble pigment that can accumulate in the stratum corneum, dermis, and subcutaneous tissue.
Effect of excessive carotene consumption
Can cause the skin to become yellowish.
Beta carotene
Associated with vitamin A and good eyesight.
Albinism
Condition in which a mutation prevents melanin production.
Albinism and skin cancer
Albinism is associated with a high risk of skin cancer.
Pale skin during shock
Can result from decreased blood flow through the dermis.
Cyanosis
Bluish skin color caused by decreased blood oxygen content.
Hair
Protects the skin and helps reduce friction.
Areas where hair is absent
Palms, soles, lips, nipples, parts of the genitalia, and distal segments of fingers and toes.
Hair follicle
Invagination of the epidermis extending deep into the dermis where hair arises.
Hair shaft
Part of the hair that projects above the skin surface.
Hair root
Part of the hair below the skin surface.
Cortex
Hard portion of hair surrounding the softer center.
Medulla
Softer center of the hair.
Cuticle
Single layer of overlapping cells covering the cortex.
Hair bulb
Area where hair is produced and which rests on the hair papilla.
Hair papilla
Extension of the dermis that protrudes into the hair bulb and contains blood vessels.
Hair growth stage
Hair forms through mitosis of epithelial cells in the hair bulb followed by keratinization.
Hair resting stage
Hair growth stops and the hair is held within the hair follicle.
Arrector pili muscle
Smooth muscle attached to a hair follicle that helps with body temperature regulation.
Two major glands of the skin
Sebaceous glands and sweat glands.
Sebaceous glands
Simple branched acinar glands that produce sebum.
Sebum
Oily, white, lipid-rich substance produced by sebaceous glands.
Function of sebum
Lubricates hair and skin, prevents drying, and protects against some bacteria.
When are sebaceous glands more active?
During puberty.
Two types of sweat glands
Eccrine and apocrine sweat glands.
Eccrine sweat glands
Simple coiled tubular glands that release sweat through merocrine secretion.
Where are eccrine sweat glands most numerous?
Palms and soles.
Apocrine sweat glands
Produce thick secretions rich in organic substances and open into hair follicles.
Locations of apocrine sweat glands
Axillary and pubic areas.
When do apocrine glands become active?
During puberty due to the influence of sex hormones.
Cause of body odor
Apocrine secretion is initially odorless but bacterial action breaks it down and produces odor.
Nails
Thin plates consisting of dead stratum corneum cells containing very hard keratin.
Nail body
Visible part of the nail.
Lunula
Whitish portion visible through the nail body.
Cuticle (eponychium)
Stratum corneum extending onto the nail body.
Nail root
Nonvisible portion extending distally from the nail matrix.
Diagnostic importance of the integumentary system
It can help with diagnosis because the skin is easily observed.
Cyanosis as a diagnostic sign
May indicate impaired circulatory or respiratory function due to decreased blood oxygen.
Jaundice
Yellowish skin color that can occur with liver damage or other causes mentioned in the module.
Hepatitis
Inflammation/damage involving the liver that can be associated with jaundice.
Burn
Injury to tissue caused by heat, cold, friction, chemicals, electricity, or radiation.