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primary organs of digestive tract
oral cavity, pharynx, esophagus, stomach, small intestine, large intestine
accessory organs of digestive tract
teeth, tongue, salivary glands, gallbladder, liver, pancreas
moist, serous, outer membrane
parietal peritoneum
moist, serous, inner membrane
visceral peritoneum
______ mesentary suspends GI tract and forms visceral peritoneum of stomach/intestines
dorsal
_____ mesentary forms lesser/greater omenta, contains lymph nodes/vessels, blood vessels
ventral
_____ omentum attaches ____ to liver
lesser, stomach
_____ omentum covers small intestines
greater
_____ anchors colon to posterior body wall
mesocolon
selective intake of food
ingestionb
breakdown of food into smaller molecules
digestion
uptake of nutrients into blood/lymph
absorption
elimination of undigested materials
defecation
physical breakdown of food into smaller particles
mechanical digestion
hydrolysis reactions for breakdown of food
chemical digestion
enzymes in saliva, stomach, pancreas, intestines break down polysaccharides into _____, proteins into ______, fats into ______ & _____, and nucleic acids into _______
monosaccharides, amino acids, glycerol, fatty acids, nucleotides
opening to throat is called
fauces
______ ligament anchors teeth into bone
periodontal
chewing aka
mastications
swallowing aka
deglutition
chemical digestion of starch begins in
mouth
salivary amylase begins ____ digestion
starch
in the stomach, _____ is activated by_____ to digest fat
lingual lipase, HCl
lubricates & binds food for swallowing
mucus
enzyme that kills bacteria
lysozyme
antibodies that inhibit bacterial growth
IgA
saliva aids swallowing by binding food together into
bolus
intrinsic salivary glands contain______ & _____
lysozyme, lingual lipase
extrinsic salivary glands
parotid, submandibular, sublingual
_____ glands of extrinsic salivary glands secrete mucous
mucous
serous glands of extrinsic salivary glands secrete _____ &_____
amylase, electrolytes
superior, middle and inferior ______ in the pharynx force food down while swallowing
constrictors
tissue layers of GI tract - deep to superficial
mucosa, submucosa, muscularis externa, adventitia/serosa
esophagus passes through ______ in the diaphram and enters the stomach at the _____
esophageal hiatus, cardiac oriface
_____ is when the tongue collects food and pushes it into the oropharynx
buccal phase
during the _______ phase, nasopharynx is blocked, epiglottis is folded back, pharyngeal constrictors push bolus down esophagus
pharyngeal-esophageal
_____ mechanically breaks up food particles, liquifies food into chyme
stomach
chemical digestion of ____ & ____ begins in the stomach
protein, fat
______ filters blood drained from stomach, before returning to the heart
liver
opening to duodenum, contains a pyloric sphincter
pylorus
Cells of Gastic Glands (stomach)
mucous, regenerative, parietal, chief, enteroendocrine cells
cells that divide rapidly and produce new cells
regenerative cells
cells in stomach that secrete HCl
parietal cells
cells in stomach that secrete pepsinogen
chief cells
cells in stomach that secrete hormones and paracrines
enteroendocrine cells
gastric juice is composed of
mostly h2o, HCl, pepsin
stomach acid that activates pepsin & lingual lipase, liquifies food to form chyme, destroys ingested bacteria/pathogens
HCl
pepsinogen is activated by ____ which converts it to _____
HCl, pepsin
when activated, pepsin can act upon pepsinogen to produce more pepsin, this is a process known as
autocatalytic process
intrinsic factor of the stomach is secreted by_____
parietal cells
_____ is essential for B12 absorption which is necessary for RBC production
intrinsic factor
_____ digests butterfat of milk in infants
gastric lipase
coagulates proteins to curdle milk
chymosin
_____ stimulates HCl & enzyme secretions, stimulates intestinal motility, relaxes iliocecal valve
gastrin
_____ stimulates gastric motility
serotonin
_____ stimulates HCl secretion
histamine
_____ inhibits gastric secretions and motility, inhibits pancreatic and gall bladder secretions
somatostatin
when food arrives at the stomach, the stomach relaxes and _______ contractions begin
peristaltic
_______ churns and mixes food with gastric juice
peristalsis
meals empty from stomach in ____ hours, high fat meals are emptied in ____ hours, liquid meals are emptied much_____
4, 6, sooner
when the _____ in medulla causes lower esophageal sphincter to relax as diaphragm and ab muscles contract, this allows for _____
emetic center, vomiting
______ of the stomach prevent gastric juices from seeping between epithelial cells
tight junctions
many ulcers are caused by _____, _____
bacteria, erosion of stomach wall by HCl and pepsin
HCl is formed when hydrogen ions and chloride ions join in the
duct of the gastric gland
number of baby teeth formed
20 teeth
bile functions to
emulsify fats
the sympathetic NS response ____ peristalsis in the GI tract
decreases
hormone that controls the release of bile from the gallbladder
cholecystokinin
____ are front teeth used for biting
incisors
organs that produce digestive enzymes
gall bladder, pancreas
absorption of vitamin B12, crucial for RBC production, requires _____
intrinsic factor
pepsin digests _____ to _____
proteins, peptides
if the parietal cells stop working you would not produce _____, _____, ____
HCl, pepsin, intrinsic factor
______ is when a portion of the stomach pushes up through the opening in the diaphragm
hiatal hernia
arrival of chyme into the duodenum over a period of time will cause
secretin release from duodenum
in the large intestine, ____ is synthesized, ____ and ____ are absorbed, ____ is secreted
vitamin K, water, electrolytes, mucous
if an adult is having diarrhea and gas after drinking milk, they are NOT producing ____ on their brush border
lactase
_____ sphincter is comprised of skeletal muscle
external anal
_____ are not directly absorbed into the blood
fatty acids
found in feces
bacteria, fiber, water, epithelial cells
removal of the _____ would have the most severe effect on the body
jejunum
increased osmolarity of fecal matter in the colon can result in
diarrhea
total volume of secretions produced by the digestive system each day
8-10 liters
____ NS of the stomach stimulates gastric secretions prior to swallowing
Enteric
during the _____ phase, stomach is controlled by the brain, which detects sight, smell, taste of food
cephalic phase
during _____ phase, the stomach controls itself and stretches as food arrives
gastric
______ phase is activated by presence of food or semidigested protein
gastric phase
when the duodenum inhibits stomach, this is called
enterogastric reflex
chyme stimulates duodenal cells to release
secretin, cholecystokinin, gastric inhibitory peptide
right and left side of liver is separated by _______ ligament
falciform
bile is produced by
hepatocyte cells
hepatic portal vein, hepatic artery, bile duct is known as
hepatic triad
hepatic portal vein & hepatic artery
bring blood to liver
______ collects bile from bile canaliculi to be secreted from the _____ in hepatic ducts
bile duct, liver
_____ filters blood to remove, glucose, amino acids, iron, vitamins, hormones, toxins, bile pigments, drugs
liver
liver secretes ____, ____, _____, ____ into blood
albumin, lipoproteins, clotting factors, angiotensinogen
liver breaks down stored _____, produces and secretes _____
glycogen, bile
condition where hepatocytes begin to die off
hepatic cirrhosis
pathway of bile
structure that stores and concentrates bile
gallbladder