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psychoactive substance
alters mood, perception, or brain functioning
polysubstance use
use of multiple substances due to combined biological, psychological, and social factors
substance use disorder
maladaptive use causing impairment or distress
substance-induced disorders
includes intoxication and withdrawal states
impaired control
using more or longer than intended, unsuccessful attempts to quit, craving
social impairment
neglecting obligations, conflict, loss of activities
risky use
using despite danger or health problems
pharmacological criteria
tolerance and withdrawal
diagnosis threshold
at least 2 symptoms within 12 months
metabolic tolerance
body increases rate of substance metabolism
pharmacodynamic tolerance
brain reduces receptor sensitivity or number
withdrawal from uppers
depressed mood, irritability, sleep and appetite changes
withdrawal from downers
nausea, pain, insomnia, anxiety
most difficult withdrawal
opiates
no withdrawal
hallucinogens
tobacco effects
stimulant, causes cancer, heart disease, and respiratory issues
stimulant effects
euphoria follewed by dysphoria, lethargy, and health risks
sedative effects
similar to alcohol, disinhibition, poor coordination, anxiety rebound
cannabis effects
mood and concentration changes, long-term attention problems
hallucinogen effects
vivid sensory experiences, possible flashbacks or psychosis
alcohol effects
short-term intoxication, long-term interpersonal, physical, and mental health damage
most addictive substances
tobacco (31.9%) and heroin (23.1%)
cultural influence on alcohol use
norms about drinking vary across history and societies
gender differences in alcohol use
men more likely to develop AUD; women drink less due to social norms and safety concerns
age of first use
early initiation (before 14) increases risk for AUD
positive beliefs about alcohol
expecting mood, social, or sexual benefits leads to heavier drinking
personality and alcohol use
high extraversion and rebelliousness increase risk
peer infleunce
exposure to peers who drink raises use likelihood, especially in extraverts
detoxifiation
medically supervised withdrawal, first treatment step
methadone
safer opioid replacement reducing withdrawal and cravings
alcoholics anonymous (aa)
peer-led, abstinence-based 12-step program; spiritual component; ~50% dropout
motivational interventions
short-term therapy to enhance readiness for change; may aim for moderation
treatment outcomes
most benefit from treatment, though relapse is common and multiple attempts may be needed