Cell Bio Exam #1

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Last updated 3:18 PM on 9/19/26
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297 Terms

1
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Who discovered cells and when?

Robert Hooke discovered cells in 1665.

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What did Robert Hooke observe under a microscope?

Thin slices of cork.

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What did Robert Hooke see in cork?

Small compartments surrounded by cell walls.

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Why did Robert Hooke call the compartments "cells"?

They reminded him of the small rooms inhabited by monks.

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What did the compartments Robert Hooke observed actually consist of?

Dead plant tissue.

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Who was Antonie van Leeuwenhoek?

A scientist who improved microscope lenses and achieved much greater magnification.

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What did Antonie van Leeuwenhoek observe in pond water?

Microscopic organisms that he called "animalcules."

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What did Antonie van Leeuwenhoek observe in pepper-water and dental plaque?

Bacteria.

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Why was microscopy important to cell biology?

Microscopes allowed scientists to actually visualize cells.

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What two limitations affected early microscopes?

Magnification and resolution/resolving power.

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What improved by the 1830s that allowed smaller cellular structures to be seen?

Compound microscopes improved enough to see structures as small as approximately 1 μm.

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What cellular structure could be clearly seen with improved compound microscopes by the 1830s?

The nucleus.

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Who proposed the original cell theory in 1839?

Schwann.

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What is the first statement of cell theory?

All organisms consist of one or more cells.

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What is the second statement of cell theory?

The cell is the basic unit of structure for all organisms.

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Who added the third statement to cell theory in 1855?

Virchow.

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What is the third statement of cell theory?

All cells arise only from preexisting cells.

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What does "omnis cellula e cellula" mean?

Essentially, every cell comes from another cell.

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What is the fourth modern cell theory statement?

Cells contain genetic information (DNA) that is passed on to the next cell generation.

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What are the four statements of cell theory?

1. Organisms are made of cells; 2. the cell is the basic unit of life; 3. cells come from existing cells; 4. cells contain and pass on DNA.

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What are four major characteristics shared by all cells?

Organizational complexity, molecular components, different sizes and shapes, and specialization by genetic programming.

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How are cells organizationally complex?

Cells are highly organized systems with specialized proteins and complex metabolism.

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What do eukaryotic cells contain that demonstrates organizational complexity?

Organelles.

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What do all cells contain as molecular components?

Carbohydrates, proteins, lipids, and nucleic acids.

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What roles do carbohydrates, proteins, lipids, and nucleic acids have in cells?

They have structural and functional roles.

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Do all cells have the same size and shape?

No; cells come in many different sizes and shapes.

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Can cells be unicellular or multicellular?

Yes, cells can be unicellular or part of multicellular organisms.

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How can cells differ in shape?

Some cells are highly specialized in shape.

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What information do genes contain?

Information and instructions for constructing cellular structures, running cellular activities, and making more cells.

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How does genetic programming produce specialized cells?

Different genetic programs allow cells to become specialized.

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What is 1 μm in meters?

1 μm = 10⁻⁶ m, or one-millionth of a meter.

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What is 1 nm in meters?

1 nm = 10⁻⁹ m, or one-billionth of a meter.

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How many nanometers are in 1 micrometer?

1 μm = 1,000 nm.

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What is 1 μm in centimeters?

1 μm = 0.0001 cm.

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What is 1 μm in millimeters?

1 μm = 0.001 mm.

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What is 1 nm in centimeters?

1 nm = 0.0000001 cm.

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What is 1 nm in millimeters?

1 nm = 0.000001 mm.

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What is an easy way to remember micro and nano?

Micro = 10⁻⁶ m; nano = 10⁻⁹ m.

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What is the approximate size of the smallest bacteria?

About 0.2-0.3 μm.

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What is the typical size of bacteria?

About 1-5 μm.

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What is the typical size of animal cells?

About 10-100 μm.

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What is the typical size of eukaryotic cells?

Generally 10-100 μm.

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How long can some elongated nerve cells become?

1 meter or more.

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How do organelles often compare in size with bacterial cells?

They are often comparable in size to bacterial cells.

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What are the three domains of life?

Bacteria, Archaea, and Eukarya.

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What are examples of Bacteria?

Escherichia coli, Pseudomonas aeruginosa, Streptococcus lactis, cyanobacteria, and Bacillus anthracis.

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What are methanogens?

Archaea that produce methane.

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Where do halophiles live?

In extremely salty environments.

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Where do thermacidophiles live?

In acidic hot springs.

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What does Eukarya include?

Protists, plants, fungi, and animals.

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What are protists?

Mostly unicellular organisms including algae, protozoans, and water molds.

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What are plants?

Multicellular, photosynthetic organisms.

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What are fungi?

Molds and mushrooms that are heterotrophic and lack chloroplasts.

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What are animals?

Multicellular organisms that ingest and process food.

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What is the typical size of Archaea?

About 1-5 μm.

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What is the typical size of Eukaryotes?

About 10-100 μm.

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What similarities do prokaryotic and eukaryotic cells share?

Both have plasma membranes, may have cell walls, have genetic material and ribosomes, and carry out cellular processes and metabolism.

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Do prokaryotic cells have a membrane-bound nucleus?

No.

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Do eukaryotic cells have a membrane-bound nucleus?

Yes.

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Where is DNA located in prokaryotic cells?

In the nucleoid region.

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Where is DNA located in eukaryotic cells?

In the nucleus.

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Do prokaryotes generally have membrane-bound organelles?

No.

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Do eukaryotes have membrane-bound organelles?

Yes.

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Do prokaryotes generally have internal membranes?

No.

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Do eukaryotes have internal membranes?

Yes.

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Do both prokaryotes and eukaryotes have ribosomes?

Yes.

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How do prokaryotes divide?

By binary fission.

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How do eukaryotic cells divide?

By mitosis or meiosis plus cytokinesis.

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What is the usual shape of prokaryotic DNA?

Circular.

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What is the usual shape of eukaryotic chromosomes?

Linear chromosomes associated with histones.

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What is the typical size of prokaryotic cells?

1-5 μm.

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What is the typical size of eukaryotic cells?

10-100 μm.

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Can prokaryotes perform exocytosis and endocytosis?

No.

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Can eukaryotes perform exocytosis and endocytosis?

Yes.

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What is an important exception to the lack of internal membranes in bacteria?

Cyanobacteria have extensive internal membranes used for photosynthesis.

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What is cell culture?

Growing cells under controlled conditions in vitro.

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What are primary cell cultures?

Cells directly isolated from human or animal tissues and then grown under controlled conditions.

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Why are primary cell cultures useful?

They more closely represent the in vivo state.

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What are HeLa cells?

An immortalized human cell line derived from Henrietta Lacks's cancer cells.

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Who was Henrietta Lacks?

An African-American woman whose cancer cells became the source of the HeLa cell line.

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What was the first immortalized human cell line?

HeLa.

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Why have HeLa cells been important?

They have been extremely important in medical research, including vaccine research.

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Were Henrietta Lacks's cells taken with her consent?

No, her cells were taken without her consent.

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When did Henrietta Lacks die?

She died in 1951 at age 31.

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What has happened to Henrietta Lacks's cells since her death?

Her cells have continued to be used in research.

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What is cytology?

The study of cellular structure, historically emphasizing observation using optical techniques.

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How did microscopy help cytology?

It overcame the problem of the extremely small size of cells and their components.

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What structures did cytology and microscopy help reveal?

Cells, nuclei, mitochondria, chloroplasts, and other cellular structures.

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What became one of the major tools of cell biology?

Microscopy.

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What three major strands does modern cell biology combine?

Cytology, biochemistry, and genetics.

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What does cytology study?

Cellular structure using microscopy and other optical techniques.

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What does biochemistry study?

Cellular structure and function at the molecular level.

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What does biochemistry examine?

Biological molecules and chemical processes.

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What methods are used in biochemistry?

Chromatography, electrophoresis, mass spectrometry, and subcellular fractionation.

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What does genetics study?

Information flow and heredity.

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What does genetics include?

The study of genes, DNA, chromosomes, and genomes.

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What created modern cell biology?

The convergence of cytology, biochemistry, and genetics.

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How can microscopy be used for disease diagnosis?

Tissue and organ sections can be examined to diagnose disease.

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How can blood smears be used medically?

They can help identify diseases.

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What parasite can microscopy identify in blood?

Malarial parasites.