2.12-DNA mutations

What is silent mutation?

When there’s no change in amino acid order due to the degenerate nature of genetic code

What is the level of severity in a silent mutation?

None

What is the outcome of the missense mutation?

Only one amino acid changes so it’s unlikely to impact overall protein structure

What is the level of severity of a missense mutation

Low-Medium

What is the outcome of a nonsense mutation?

The introduction of a stop codon in the middle of the base sequence and no protein is produced

What is the severity of a missense mutation?

High

What is the outcome of a frameshift mutation?

The deletion or insertion of a base which then alters the order of all amino acids downstream from the mutation, producing a non-functioning protein

What is the level of severity of a frameshift mutation?

High