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Dental caries
An infectious, multifactorial, transmissible disease caused by bacteria that demineralize tooth structure.
What are the primary factors of caries?
Susceptible tooth/host,Cariogenic microorganisms,Fermentable carbohydrates,Time/frequency,Saliva can modify the process
Cariogenic bacteria
Bacteria that can contribute to tooth decay by producing acids from carbohydrates.
Streptococcus mutans
Major cariogenic bacterium associated with dental caries.
Fermentable carbohydrates
Carbohydrates bacteria can metabolize to produce acids.
Cariogenic
Capable of promoting dental caries
Cariostatic
Does not significantly lower plaque pH or promote caries.
Noncariogenic
Does not promote caries because oral microorganisms cannot readily metabolize it.
Anticariogenic
Helps prevent or reduce caries activity.
Acidogenic
Produces acid or causes plaque/salivary pH to decrease.
Critical pH
Approximately 5.5 for enamel; below this, demineralization can occur.
Demineralization
Loss of minerals from tooth enamel/dentin due to acids.
Remineralization
Replacement of minerals into tooth structure.
Casein
Milk protein that can help protect enamel from demineralization.
Food source: cheese.
Saliva
Helps lubricate, cleanse, buffer acids, provide antibacterial action, aid remineralization, and facilitate taste.
Salivary buffer
Substance in saliva that helps neutralize acids.
Resting saliva pH
Approximately 6.5–7.0.
Bicarbonate
Major salivary buffer that helps neutralize acids.
Salivary flow
Increased by firm, coarse, fibrous foods.
Retentive food
Food that sticks to teeth and remains in the mouth longer.
Highly retentive foods
crackers, potato chips, pretzels, bakery products.
Frequency of intake
More frequent carbohydrate exposure = more frequent drops in plaque pH = greater caries risk.
Salivary pH after carbohydrate intake
Can remain below the critical level for approximately 40 minutes.
Carbohydrates are?
Organic compounds made of carbon, hydrogen, and oxygen; primary source of energy.
Energy from carbohydrate ‘IMPORTANT’
4 kcal/g
Monosaccharide
1 sugar
Disaccharide
2 sugars
Polysaccharide
Complex carbohydrate made of many sugar units.
Glucose
Main blood sugar; major fuel for the brain and body.
Fructose
Fruit sugar; naturally found in fruits and honey.
Galactose
Milk sugar component; combines with glucose to form lactose.
Sucrose — Glucose + fructose.
Table sugar. Most associated with dental caries. (disaccharide)
Lactose — Glucose + galactose.
Milk sugar. (disaccharide)
Maltose — Glucose + glucose.
Found in malt/beer products. (disaccharide)
Starch
Plant storage form of glucose. rice, potatoes, pasta, legumes. (poly)
Glycogen
Storage form of glucose in animals/humans.
Stored primarily in liver and muscles. (poly)
Fiber
Carbohydrate that is not completely digested by humans.
(poly)
Dietary fiber
Naturally occurring fiber in plants; generally not digested. (poly)
Functional fiber
Isolated/added fiber that has beneficial physiological effects.
(poly)
Total fiber
Dietary fiber + functional fiber (poly)
Sugar alcohols
Sweeteners ending in -ol that generally do not promote tooth decay. '
XylitOL,SorbitOL,MannitOL
Xylitol
Five-carbon sugar alcohol with anticariogenic properties.
Non-nutritive sweeteners
provide little/no energy and are not readily metabolized by cariogenic bacteria.
Saccharin,Aspartame,Sucralose,Acesulfame potassium,Neotame
Saccharin
Artificial/non-nutritive sweetener found in products such as Sweet'N Low.
Aspartame
Non-nutritive sweetener found in Equal/NutraSweet; contains phenylalanine.
PKU (phenylketonuria)
Genetic condition in which phenylalanine cannot be properly metabolized.
People should avoid aspartame.
Sugar alcohol side effects
Large amounts can cause gas, bloating, and diarrhea because they are incompletely absorbed.
Cariostatic foods
Do not significantly lower plaque pH, Meat,Fish,Eggs,Nuts,Seeds,Fats/oils
Noncariogenic foods
Not readily metabolized by oral bacteria and therefore do not promote caries.
Raw vegetables,Nutts,Cheese
Anticariogenic foods
Can actively help protect against caries.
Xylitol-containing foods,Certain cheeses,Foods containing protective compounds
Cocoa factor
Component of cocoa associated with anticariogenic properties.
Glycyrrhiza
licorice
Perimolysis
Erosion of teeth associated with repeated vomiting, commonly seen with bulimia.
Vitamin C deficiency
Can predispose a person to gingival inflammation/gingivitis.
Vitamin C
Important for collagen formation and maintenance of connective tissues.
Necrotizing gingivitis/periodontitis
Severe periodontal infection associated with factors such as stress, smoking, poor oral hygiene, and nutritional deficiencies.
Nutritional deficiencies associated with necrotizing gingivitis:
Protein,Vitamin C,B vitamins
Vitamin A
Important for epithelial tissues and oral tissue development.
Vitamin D
Important for calcium absorption and mineralization.
Vitamin E
Antioxidant; contributes to tissue maintenance.
B-complex vitamins
Important for metabolism and tissue health.
Causes of xerostomia
Medications
Sjögren syndrome
Diabetes
Head/neck radiation
Stress/anxiety
Certain systemic diseases
Anosmia
loss of smell that can reduce the ability to taste.
Hypogeusia
Decreased taste ability
Hypergeusia
Increased taste sensitivity
Dysgeusia
Altered/distorted taste
Metabolism,Anabolism,Catabolism
how cells acquire, transform, store, and use energy.
Builds larger/complex molecules from smaller molecules.
Breaks larger molecules into smaller molecules.
Biotransformation
Chemical modification of substances by the body, especially through metabolic processes
Carbohydrate,protein,fat,alcohol how many kcal?
4,4,9,7
Basal Metabolic Rate (BMR)
Energy needed to maintain basic life functions while at rest.
Thermic Effect of Food (TEF)
Energy required to digest, absorb, and process food.
EER (Estimated Energy Requirement)
Energy intake predicted to maintain energy balance.
BEE (Basal Energy Expenditure)
Energy required to maintain basic bodily functions.
Amenorrhea
Absence/loss of menstrual periods.
Lanugo
Fine, thin body hair that can develop with severe malnutrition, classically associated with anorexia nervosa.
Cheilosis
Dry, cracked, inflamed lips.
Accessory organs
Salivary glands,Liver,Gallbladder,Pancreas
Bolus
Mass of chewed food mixed with saliva that is ready to be swallowed.
Chyme
Semi-liquid mixture produced when food mixes with gastric secretions in the stomach.
Amylase, Pancreatic amylase
Enzyme that begins carbohydrate digestion by breaking down starch
Continues carbohydrate digestion in the small intestine
Pepsin
Enzyme that breaks proteins into smaller fragments
Gastric lipase
Enzyme involved in digestion of short- and medium-chain triglycerides.
Villi
Fingerlike projections in the small intestine that increase surface area for nutrient absorption.
Peristalsis
Wave-like muscular contractions that move food/feces through the GI tract.
Large intestine
Primarily absorbs water/electrolytes and forms/stores feces; has little digestive function.
Dipeptide
2 amino acids.
Tripeptide
3 amino acids.
Oligopeptide
Small chain of amino acids.
Protein turnover
Continuous breakdown and replacement of body proteins.
Nitrogen balance
Relationship between protein breakdown and protein synthesis.
Positive nitrogen balance
More protein is being built than broken down.
Sarcopenia
Age-related loss of muscle mass and strength
Complete protein
Contains all 9 essential amino acids in adequate amounts
Protein complementation
Combining incomplete proteins so their amino acid profiles complement each other.
Examples:
Rice + beans
Peanut butter + toast
Lentils + seeds
Protein DRI
0.8 g/kg/day for healthy adults.
Protein-energy malnutrition (PEM)
Deficiency of protein and/or energy.
Marasmus
Chronic form of PEM
Causes:
Long-term inadequate energy/protein intake
Commonly associated with children 6–18 months in developing countries.
Kwashiorkor
Acute/severe protein deficiency
Commonly associated with children 18–24 months.
Findings:
Edema
Failure to grow
Delayed tooth eruption
Enamel hypoplasia
Edema, Enamel hypoplasia
Abnormal accumulation of fluid in tissues
Defective/incomplete development of enamel.
Lacto-ovo vegetarian
Lacto-vegetarian
Ovo-vegetarian
Eats dairy + eggs, but no meat/fish/poultry
Eats dairy, but no eggs/meat/fish/poultry.
Eats eggs, but no dairy/meat/fish/poultry.