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Blood vessels form a _______ transport system
closed
Blood moves in a cycle: Heart → ______ → _______ → Capillaries → ______ → Veins → _____
arteries; arterioles; venules; heart
Vessels differ in _________, but all serve the same goal: ______ & ______ blood efficiently
structure; deliver; return
carry blood away from the heart
arteries
return blood to the heart
veins
thin vessels where exchange of gases, nutrients, and wastes occurs
capillaries
what circuit goes from the right side of the heart → Lungs → Back to left side?
pulmonary circuit
function of the pulmonary circuit
exchange CO2 for O2
what circuit goes from the left side of the heart → Body tissues → Back to right side?
systemic circuit
function of systemic circuit
deliver O₂ and nutrients; remove wastes
arteries ________ transport oxygen-____ blood
usually; rich
in arteries, ____ pressure, _______ lumen (opening)
high; smaller
veins _________ carry oxygen-____ blood
usually; poor
in veins, ______ lumen and contain valves to prevent _______
larger; backflow
3 tunics of BV walls
intima, media, externa
tunica intima contain ___________ (smooth lining) + ____ connective tissue
endothelium; thin
tunica ______ reduces friction for blood flow
intima
tunica ______ lines the lumen (inside space of the vessel).
intima
tunica media contain _______ muscle + ______ fibers
smooth; elastic
tunica _______ allows vasoconstriction (narrowing) & vasodilation (widening)
media
tunica _____ are thicker in arteries
media
tunica externa contains connective tissue with _______ & ______ fibers
collagen; elastic
tunica ______ protects and anchors vessel to surrounding tissue
externa
Endothelium regulates exchange between _____ and _______
blood; tissues
exchange for food and oxygen: into _______
tissues
exchange for wastes and CO2: into _____
blood
vascular endothelium produces compounds that control: vasodilation/_____________, Inflammation, ____ formation (injury response), _______ muscle activity
vasoconstriction; clot; smooth
Small arteries; regulate flow to capillaries
arterioles
Small veins; return CO₂-rich blood
venules
Veins have low ________ → need help _________ blood to heart
pressure; returning
in veins, blood flows ________ gravity, aided by: _______ and _______ muscle contractions
against; valves; skeletal
______ lumen allows more blood flow at _____ pressure
large; lower
factors aiding venous return: ________ pump, _______ pump, and ____________
respiratory; muscular; vasoconstriction
respiratory pump: Breathing changes _____ pressure → pulls blood _______ the heart
chest; toward
Muscular Pump: ________ muscles contract → ______ (milking) veins and push blood forward.
skeletal; squeeze
vasoconstriction – Veins narrow under ___________ control → blood moves ______ toward the heart.
sympathetic; faster
blood flows because of pressure _________
gradients
venous return depends on: ___ and _______ _____ pressure
CVP; right atrial
pressure in the large veins near the heart.
central venous pressure
if atrial pressure rises too much (like in heart failure), venous return decreases.
right atrial pressure
_______ venous return → stretches atrial walls → supports ______ output (Frank–Starling law).
increased; cardiac
venous return is also influenced by blood _______
volume
_____ blood volume (hemorrhage, dehydration) = ____ venous return
low; low
____ blood volume (fluid overload, pregnancy) = ____ venous return
high; high