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What do rumen microbes need to avoid the production of ammonia?
energy and nitrogen in a similar ratio
When ammonia is absorbed into portal vein where does it travel to?
the liver.
What is NH3 converted to in the liver?
urea because NH3 is toxic. It is converted via the urea cycle
Is the urea cycle energy costly?
yes 1 urea= 3 ATP
What are the two fates of urea?
excreted in milk/urine
urea recycles
What is urea recycling?
urea arrives at rumen
urease breaks down urea into ammonia
ammonia is used for microbial protein
Where do amino acids go after being absorbed by the portal vein?
the liver then peripheral circulation
What are the 3 fates of A.A after arriving at the peripheral circulation?
A.A specific functions
energy from the TCA cycle only in negative energy balance
protein synthesis in mammary gland/muscle
What is A.A balancing?
to much will be excreted. Too little can be limiting
Does nitrogen require energy to be excreted?
yes
How do you ensure A.A can be absorbed in the S.I?
can use rumen protected A.A to avoid microbes from degrading the A>A
Why do you use an adaptation period to get animals use to urea?
because it is toxic in high levels
What are the two classifications of vitamins?
fat soluble and h2o soluble
How are fat soluble vitamins stored in the body?
use dietary fat to be absorbed via a micelle formation and blood transport via chylomicrons
Do fat soluble vitamins function like lipids?
yes because they can be stored in the body for a long time
What are the 7 characteristics of vitamins?
Organic components required in small amounts for reactions
Can be destoryed by heat ligh or metals
Vitamins cannot be synthesized by animal cells
B+K microbes can synthesize
vitamins A C E are antioxidants
Vitamins from diet must be converted to active form
Too much or Too little can be toxic
What is vitamin A important for?
epithelial lining, immune system, and vision
What does vitamin A deficiency cause?
skin problems
Does vitamin A act as an antioxidant?
yes so add during parturition exercise and producing animals
What is vitamin D important for?
bone growth, calcium/phosphorus absorption in the small intestine
What does vitamin D deficiency cause?
osteomalacia, rickets, milk fever
What is vitamin E important for?
antioxidant
What is a common vitamin E deficiency in sheep?
white muscle disease.
What is vitamin K important for?
blood clotting
What is vitamin B1 important for?
conversion of pyruvate to acetate to generate energy
What is a deficiency sign of B1?
increased blood pyruvate
What is B2 and B3 important for?
formation of energy and redox cofactors for TCA cycle
What is deficiency signs of vitamin B2 and B3?
reduced growth and or paralysis
What is vitamin B5 important for?
component of co-enzyme A
What is a vitamin deficiency sign of vitamin B5?
goose stepping
What is vitamin B6 important for?
A.A metabolism. transamine removes N2 to make a keto acid. W
What is vitamin B6 deficiency signs?
neurological issues because vitamin B6 helps with myelin formation
What is vitamin B8?
biotion important for gluconeaogensis/ fatty acid synthesis
What is deficiency signs of B8?
dermatitis/ alopecia
What is b9?
folic acid works with b12 for AA synthesis.
what is the loss of activity of vitamins and minerals?
if vitamins and minerals are kept together vitamins will decrease activity
What is organic type of mineral?
mineral plus amino acid this prevents degradation
How many minerals are essential?
22
Where are minerals stored?
in the body (liver)
What are the two types of mineral absorption?
active and passive transport
What aids active transport of minerals?
A. A carrier
How does the p.h of the gi track affect absorption?
hcl changes the charges of minerals and can increase absorption
What are macro minerals?
minerals need in conc. > 100 ppm
ex: ca, phos, mg, k
what are trace/micro minerals?
needed in conc. < 100 ppm
ex: fe, selenium, sinc, copper
What ratio is needed for calcium and phosphorus?
2:1 with more calcium
Calcium is important for what?
blood clotting/bone
What is phosphorus important for?
bone formation/ enegy.
What is forage high in?
calcium
What is grain high in
phosphorus
What is selenium?
essential with a small optimal range. can accumulate in plants
What are signs of selenium toxicity?
sudden death
What are signs of selenium deficicney?
white muscle disease typically in grazing livestock
what are signs of a copper deficiceny?
depigmentation
What are signs of a zinc deficiency?
parakeratosis skin issues
What is vitamin D required for?
calcium absorption in G.I track. W
What happens if there is no vitamin D?
calcium is mobilized from bones W
What does copper toxicity cause in sheep?
liver issuesW