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Beta lactam drugs
Penicillins
target cell wall by inhibiting transpeptidases and PBPs
Bacteriodcidal
Beta lactamase inhibitors
CAST: clavulanic acid, sulbactam, tazobactam
NOT antibiotics
Tetracyclines
Doxycycline
Target protein synthesis by binding reversibly to 30S (prevents access of tRNA)
Not for children or pregnant women
Macrolides
Azithromycin and erythromycin
Target protein synthesis by binding to 50s (inhibits translocation + transpeptidases)
Antivirals
Acyclovir
Inhibits viral DNA synthesis
Good for herpes viruses
Methotrexate
Inhibits dihydrofolate reductase (inhibits formation of folate)
Statins
Inhibit rate-limiting step of cholesterol synthesis: HMG CoA reductase