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Iron Deficiency Anemia
Smear Findings
mild to severe microcytic/hypochromic
ovalocytes/pencils
NO RBC INCLCUSIONS
MCV
<82.0


Megaloblastic Anemia
Smear Findings
H: Howell-Jolly Bodies
H: Hyper-segmented Neutrophils
O: Ovalocytes
T: Teardrops
Other Findings
giant platelets
schistocytes
pappenheimer
Basophilic stippling
MCV
>98.0

Hereditary Spherocytes
Smear Findings: few to many spherocytes
MCV: 82 - 98

Warm Autoimmune Hemolytic Anemia
Smear Findings
Spherocytes
Looks similar to H. Spherocytosis but positive DAT

Hereditary Stomatocytosis
Smear Findings: few to many stomatocytes
MCV: 82-98

Sickle Cell Disease
Smear Findings:
targets
sickle cells
nucRBC
polychromasia
RBC inclusions: HJB, Paps, Baso Stip
Hemoglobin SC Disease
Smear Findings
target cells
many bizarre SC crystals
if any sickles are present, it’s NOT Hgb SC
MCV: 82-98

Hereditary Ovalocytosis
Smear Findings
few to many ovalocytes
MCV: 82-98
