CHRONIC VENOUS INSUFFICIENCY (CVI) MEDS

THIS COVERS ALL MEDICATIONS FOR VENOUS ISSUES (CVI, DVT, VARICOSE VEINS, ETC)

what type of anticoagulant inhibits clot formation and has the body absorb an existing clot over a long period of time?

unfractionated heparin

what type of anticoagulant simply inhibits clot formation?

low molecular weight heparin (LMWH)

what type of anticoagulant exerts an anticoagulant effect and prolongs clotting time?

Xa inhibitors

what type of anticoagulant inhibits the production of 4 Vitamin K dependent clotting factors?

warfarin

what type of anticoagulant dissolves existing thrombi and impairs coagulation?

thrombolytics

Heparin (drug class)

unfractionated heparin

enoxaparin, dalteparin, & ardeparin (drug class)

low molecular weight heparin (LMWH)

rivaroxaban, apixaban, edoxaban, & dabigatran (drug class)

Xa inhibitors

Coumadin (drug class)

warfarin

streptokinase & urokinase (drug class)

thrombolytics

Heparin Induced Thrombocytopenia (HIT) & Bleeding (side effects)

unfractionated heparin

Bleeding & Thrombocytopenia (side effects)

low molecular weight heparin (LMWH)

Significant risk of hemorrhage & Intracranial Bleeding (side effects)

thrombolytics

what is the specific lab monitored for heparin?

Partial Thromboplastin Time (PTT)

what is the antidote for excessive bleeding on heparin?

protamine sulfate

what is the benefit of using Xa inhibitors?

they do not require frequent lab monitoring, few med interactions, & little to no food interactions

what is the antidote for excessive bleeding on Xa inhibitors?

andexanet alfa

what lab needs to be closely monitored on warfarin?

prothrombin time/international normalized ratio (PT/INR)

what is the antidote for excessive bleeding on warfarin?

vitamin K

True or False: Thrombolytics have a narrow time window in which they can be administered.

True