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What are the interconnected tube tissue types in the female reproductive tract?
Mucosa (inner), Submucosa, Muscularis, Serosa (outer)
What are the three secretory epithelium found in the mucosa?
Ciliated simple columnar→ moves materials
Non-ciliated simple columnar→ produces fluid
Stratified Squamous→ protection during copopulation
What is the submucosa?
houses blood vessels, nerves and lymphatics, supports mucosa
What are the two types of muscularis?
Circular smooth muscle (weak) and longitudinal smooth muscle (strong for birth)
What is serosa?
outer surface covering, single cell layer of squamous epithelium
What are the three layers of the broad ligament?
Mesovarium, mesosalpinx, mesometrium
What is the mesovarium?
cranial portion, houses vessels and nerves that supply the ovary
What is the mesosalpinx?
supports the oviduct, orientates oviduct to catch the oocyte
What is the mesometrium?
largest portion, supports uterine horn and body
How does the broad ligament contribute to embryonic development?
develops retroperitoneal, pushes into body cavity, 2 layers with continuous peritoneum
What is the ovary?
produces female gametes (ova), secrete hormones
What does the follicle secrete?
estrogen
What does the corpus luteum secrete?
progesterone, relaxin, activin, oxytocin, inhibin
What are the layers of the ovary?
tunica albuginea, ovarian cortex, ovarian medulla
What is the tunica albuginea?
outer connective tissues, single layer of cuboidal cells
What is the ovarian cortex?
houses oocytes and corpora lutea and corpora albicana
What is the ovarian medulla?
has vasculature, nerves and lymphatics, composed of dense connective tissue
What are the differences of the ovaries in mares?
medulla is outer and cortex is inner, has ovulatory fossa, CL grows inward
What are the primordial follicles?
microscopic, oocyte surrounded by single layer of squamous cells, finite at birth in females
What are the primary follicles?
more mature, surrounded by single layer of cuboidal epithelium
What is the secondary follicles?
2 or more layers of follicle cells, surrounded by zona pellucida
What is the function of Zona Pellicidia?
prevents multiple sperm from entering
What is the antral follicle?
antrum present (follicular fluid filled cavity), develops three layers (teca externa, theca interna, granulosal cell layer)
What is the graafin follicle?
visible to naked eye, vary in size, fully developed three layers (theca externa, theca interna, granulosal cell layer)
What is the ovulating follicle?
few reach this stage, exits out of the ovary
What is the theca externa?
loose connective tissue that surrounds and supports the follicle
What is the theca interna?
produces androgens under the lutelysing hormone
What is the granuosal cell layer?
produce estrogen, inhibin and follicular fluid under control of follicle stimulating hormone, controls oocyte maturation
What is the corpus hemorrhagicum?
follicle collapses and becomes corpus during ovulation, small blood vessels rupture
What is the corpus luteum?
produces progesterone to maintain pregnancy
What is the corpus albicans?
only forms if not pregnant, the scar tissue after CL heals, can have more than one (does not heal by next cycle)
What are the structures in the oviduct?
infundibulum, ampulla, isthmus
What is the infundibulum function?
funnel shaped to catch oocyte, have fimbriae to increase SA, opening is ostium
What is the function of the ampulla?
thick middle portion, largest in length and diameter, fern like mucosal folds with ciliated epithelium (help sperm and egg meet), site of fertilization
What is the function of the isthmus?
connect the uterus-uterotubal junction, fewer mucosal folds, only allows fertilized ova to pass through
What are the tissue layers of the oviduct function
muscularis→ transports oocytes and sperm to site of fertilization
mucosa→ secretions provide optimum environment
fertilization and feeds embryo until it travels to uterus
What are some species-specific oviduct tissue layer functions?
Cattle→ kinks at uterotubal junction
Swine→ Constriction
What is the uterus?
connects the oviduct to cervix, contains horns and body
What is the function of uterus?
sperm transport, luteolysis and control of cyclicity, environment for pre-attachement of embryo, maternal contribution to the placenta, expulsion of the fetus and placenta
What are the layers of uterus?
perimetrium, myometrium, endometrium
What is the perimetrium?
serosal layer, continuous with mesosalpinx, thin and almost transparent
What is the myometrium?
longitudinal and circular muscle, provides motility for uterus contractions, high uterine tone (under influence of estrogen)
What are the 2 layers of endometrium and its function?
mucosal and submucosal layer
produce prostaglandin F2a which causes luteolysis if not pregnant, maintain proper environment and nutrients for embryo
What is the uterine mucosal layer function?
secretes material for embryo and sperm viability, surficial uterine glands develop
What is the uterine submucosal layer function?
connective and supporting tissue for uterine glands
What are uterine glands?
penetrate and coil under estrogen, secrete histrotroph (nutrients to embryo until placenta develops) under progesterone
What are the differences in placenta for species?
Ruminants→ caruncles (vascularized bumps that are part of the placenta)
Nonruminants→ placenta folds (look like scars)
What is the cervix?
thick walled, connects uterus to vagina, lubrication and flushing, barrier for sperm transport, mucus plug barrier during pregnancy
What are the differences of the cervix based on species?
cow and ewe→ 3 rings
mare→ loose folds
sow→ interdigitated rings
What is the vagina?
copulatory organ and birth canal, poorly developed mucosal layer, highly developed mucosal epithelium
What are the differences in epithelium based on location in vagina?
cranial vagina→ columna epithelium
caudal vagina→ stratified squamous epithelium
What is the vulva?
external portion of repro tract, consist of labia major and minor
What are the structures of the vulva?
Perineum→ surrounds vulva and anus
Clitoral Fossa→ houses the clitoris
Vestibular glands→ secretes mucous like material during estrus
What is the function of the ductus deferens?
transports sperm to the accessory sex glands
What is the function and types of the accessory sex glands?
produces seminal plasma
seminal vesicles, prostate, bulbourethral
What is the spermatic cord?
what suspends the testis, houses the pampiniform plexus, cremaster muscle
How cool does the testes need to be to keep sperm viable?
4-6 degrees Celsius
What are the structures that help cooling of the testes?
pampiniform plexus, cremaster muscle, scrotal skin, tunica dartos
How does the pampiniform plexus monitor temperature?
the intertwined of arteries and vein transfers the arterial heat to the veins (going back to the heart)= counter current heat exchange
Does pulse pressure eliminator affect temperature?
NO, the convolution for arteries just slow blood flow down no heat is exchanged
How does the cremaster muscle affect temperature?
muscle that supports the testes, contracts and relaxes (facilitating blood flow movement) but is straited= not able to sustain contractions
What is the scrotum and its correlating layers?
protects, supports and helps control temp for testes
skin, tunica dartos, scrotal fascia (inner), parietal tunica vaginalis(inner)
What does the scrotum skin do?
has sweat glands for evaporative cooling as the thermosensitive nerves send signals to hypothalamus to initiate panting and sweating
What is the tunica dartos?
smooth muscle that contracts to alter the closeness of scrotum to body, controlled by sensory nerves and testosterone (contractile characteristics)
What are the roles of the testes?
produce spermatozoa, testosterone, inhibin, estrogen and proteins (sperm function), fluid for sperm suspension
What are the areas of the testes?
testicular capsule, parenchyma, mediastinum
What is the testicular capsule?
houses the outer (visceral tunica vaginalis) and inner (tunica albuginea)
What does the tunica albuginea do?
connective tissue and smooth muscle whose rhythmic contractions facilitate movement of sperm and blood flow
What is the parenchyma?
contains the tubular compartment and interstitial compartment
What does the tubular compartment of the parenchyma contain?
seminiferous tubules and Sertoli cells
What does the interstitial compartment contain?
blood vessels, connective tissue, lymphatics, nerves, leydig cells (produce testosterone)
What is the mediastinum?
connective tissue core, houses rete tubules, denseness keeps tubules from collapsing
What is the function of the rete tubules?
tiny channels that carry sperm out of testes into the efferent duct system
What receptors do Sertoli cells have?
FSH, testosterone
What are the structures of the seminiferous epithelium?
basement membrane in basal compartment, deep adluminal compartment, peripheral adluminal compartment
What is the basement compartment hold?
spermatogonia
What process changes spermatogonia to primary spermatocytes
mitosis
How do spermatocytes travel from basal compartments to the adluminal compartments?
Sertoli tight junctions (blood testes barrier)
What does the blood testes barrier block?
blocks immune cells (macrophages and lymphocytes) and immunoglobins, prevents autoimmune reactions destroying spermatozoa
What process occurs in the deep adluminal compartment?
meiosis (primary to secondary) also form spermatids
What happens in the peripheral adluminal compartment?
nucleus elongation and cytoplasm invasion from the sertoli cells, become spermatozoa
What is the epididymis?
Where sperm become motile, gain ability to fertilize and stored (tail), more time spent there it will be a decrease in quality, sperm is constantly being voided to eliminate “build-up”
What happens to the spermatozoa in the epididymis head?
not motile or fertile, contains proximal cytoplasmic droplet, low disulfide crosslinking
What happens to the spermatozoa in epididymis body?
some motility and fertility (can bind to oocyte but not well), translocating cytoplasmic droplet, medium→high disulfide crosslinking
What happens to the spermatozoa in the epididymis tail?
motility, fertile, distal droplet, high disulfide crosslinking, can bind to oocytes
What is seminal plasma?
provides fluid for delivery, fructose (energy source), uterine inflammation that prepares the uterus for copopulation
What accessory sex gland secrets the most seminal plasma?
seminal vesicles
What does the accessory sex gland ampulla do?
enlarge the ductus deferens
What does the accessory sex gland bulbourethral do?
provides gel fraction (specifically boars)
What are the properties the seminal plasma for boars and stallions?
coagulation properties
What are characteristics of the penis?
copulatory organ, consist of base, shaft, glans penis
What is the fibroelastic penis?
bulls, boars, rams
limited erectile tissue (no change in diameter), S-shaped (contract= inside body, relaxed= outside), corpus cavernosum, corpus spongiosum
What is the musculovascular penis?
stallion
arterial rush→ penis→ expansion= vein constriction, change in diameter, corporal sinusoids
What is the route of sperm from creation to ejaculation?
basal compartment→ deep adluminal compartment→ peripheral adluminal compartment→ rete tubules→ efferent duct system → epididymal duct→ epididymis head → body→ tail → ductus deferens→ accessory sex glands→ penis→ glans penis→ ejaculation
What is the route of the ovary from creation to fertilization?
primordial follicles → primary follicles → secondary follicles → antral follicle → graafin follicle→ ovulating follice→ infundibulum→ ampulla (fertilized)→ isthmus→ uterine horns→ uterine body