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Saprophytes
these microorganisms are nonpathogenic; their natural habitat is dead organic matter
parasites
unicellular or metazoan organism living in or on an organism of another species (host) on the expense of the host
commensals
normal inhabitants of skin and mucosa; the normal flora is thus the total ——- population
pathogenic microorganisms
classic disease-causing pathogens
opportunist or facultatively pathogenic microorganisms
can cause disease in immunocompromised individuals given an “oportune” situation; theseare frequently germs of the normal flora or occasionally from the surrounding environment, animals or other germ carriers
pathogenicity
capacity of a pathogen species to cause disease
virulence
sum of the disease-causing properties of a strain of a pathogenic species
incubation period
time between infection and manifestation of disease symptoms; this specific disease characteristic can be measured in hours, days, weeks, or even years
prepatency
a parasitological term; time between infection and first appearance of products of sexual re-production of the pathogen (e.g., worm eggs in stool of a host with helminthosis)
infection spectrum
the totality of host species “susceptible” to infection by a given pathogen
minimum infective dose
smallest number of pathogens sufficient to cause an infection
mode of infection
method or pathway used by pathogen to invade
contamination
microbiological presence of microorganisms on objects, in the environment, or in samples for analysis
colonization
presence of microorganisms on skin or mucosa; no penetration into tissues; typical of normal flora; pathogenic microorganisms occasionally also show colonization behavior
infection
invasion of a host organism by microorganisms, proliferation of the invading organisms, and host reaction
inapparent (or sub clinical) infection
infection without outbreak of clinical symptoms
infectious disease (or clinical infection)
infection with outbreak of clinical symptoms
probability of manifestation
frequency of clinical manifestation of an infection in disposed individuals
endogenous infection
infection arising from the colonizing flora
exogenous infection
infection arising from invasion of host by microorganisms from sources external to it
nosocomial infection
infection acquired during hosptalization
local infection
infection that remains restricted to the portal of entry and surrounding area
generalized infection
lymphogenous and/or hematogenous spread of invading pathogen starting from the portal of entry; infection of organs to which pathogen shows a specific affinity
sepsis
systematic disease caused by microorganisms and/or their toxic products; there is often a localized focus of infection from which pathogens or toxic products enter the blood stream continuously or in intermittent phases
transitory bacteremia/viremia/parasitemia
brief presence of microorganisms in the bloodstream
superinfection
occurrence of a second infection in the course of a first infection
relapses
series of infections by the same pathogen
reinfection
series of infections by different pathogens