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warfarin is an ____
anticoagulant
warfarin has a ___ half life
long
warfarin is monitored by _____ (2)
PT and INR
for warfarin, PT should be ___ times the control
1.5-2
for warfarin, INR should be ___ times the control
2-3
most common adverse effect of warfarin
bleeding
warfarin has many ___
drug interactions
heparin has a ___ half life
short
heparin requires ____
intensive monitoring
antidote for heparin
protamine sulfate
what value is monitored for heparin
aPTT
adverse effects of heparin (4)
hemorrhage
hematoma
thrombocytopenia
hypersensitivity
what IV med is high alert
heparin
low molecular weight heparin is called
enoxaparin (lovenox)
Pradaxa is a ___ inhibitor
thrombin
Rivaroxaban is a ___ inhibitor
factor Xa
main indication for antiplatelets
prevent arterial thrombosis
3 antiplatelets
aspirin
adenosine diphosphate antagonists
IIb/IIIa receptor antagonists
aspirin persists for ___ days
7-10
daily dose of aspirin
81 mg
adenosine diphosphate antag are ____
prodrugs
clopidogrel (plavix) is an ___
adenosine diphosphate receptor antag
abciximab (reopro) is a ___
glycoprotein IIb/IIIa antagonist
IIb/IIIa antag are only adminstered ___
IV
IIb/IIIa double the risk of ___
major bleeding
thombolytic drugs ar emeant to be used ___
ASAP
major concern of thrombolytics?
bleeding
ending for thrombolytics:
-ase