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Communicable disease
Disease that can be transmitted from one host to another
Noncommunicable disease
Disease not spread from host to host; usually environmental, genetic, or from normal microbiota
Notifiable disease
Disease required by law to be reported to health authorities for monitoring
Epidemic
A sudden increase in disease cases above normal levels in a population
Common source epidemic
Many people infected from one shared source (e.g., contaminated water)
Propagated epidemic
Disease spreads person-to-person over time
Index case
First identified case in an outbreak
R0 (Basic reproduction number)
Number of people one infected person will pass the disease to on average
Endemic
Disease occurs at a constant, predictable rate in a population
Pandemic
Worldwide epidemic affecting multiple countries or continents
Sporadic
Disease occurs only occasionally in low numbers
Incidence rate
Number of new cases in a population during a defined time period
Prevalence rate
Total number of existing cases at one point in time
Virulence factor
Microbial trait that allows infection or damage to host tissues
Opportunistic pathogen
Causes disease only when host defenses are weakened
Reservoir
Where the pathogen normally lives and multiplies
Zoonosis
Disease that spreads from animals to humans
Infectious dose
Number of microbes needed to establish infection in a host
Portal of entry
Where pathogens enter a new host (e.g., respiratory tract, mucous membranes)
Portal of exit
Route pathogens leave the host (e.g., droplets, blood, feces)
Direct contact
Transmission through physical contact with infected host
Droplet transmission
Transmission via respiratory droplets traveling short distances
Vertical transmission
Transmission from mother to fetus or newborn
Fomite
Nonliving object that spreads pathogens
Vehicle
Food, water, or blood that can carry pathogens and allow them to multiply
Vector
Living organism (often an arthropod) that transmits pathogens
Biological vector
Pathogen reproduces inside the vector
Mechanical vector
Vector physically carries pathogen on surface
Healthcare-associated infection (HAI)
Infection acquired while receiving medical care
Herd immunity
When enough people are immune to a disease, reducing spread and protecting susceptible individuals