Integrated Biomedical Sciences and Biochemistry in Oral Health and Disease

What is D1 BMSC 804 course about?

Foundational material and basic science integration with the musculoskeletal block, human systems at both macroscopic and microscopic levels

What is D2 BMSC 805 course about?

Expanding on foundational aspects of anatomy, biochemistry, histology and physiology across the body system, such as cardiopulmonary, renal/endocrine/reproductive, gastrointestinal and application to dentistry.

What are main influencers of oral health and overall development or oral diseases and conditions?

Diet and nutrition

What is the caries disease process?

Biofilm-mediated, sugar-driven, multifactorial, and dynamic in the phasic demineralization and remineralization of dental hard tissues.

What is the relationship between carbohydrates and dental caries?

Depending on which type of carbohydrate consumed, cariogenic potential varies on efficient it can be metabolized by the bacteria that ferment it.

What is the primary necessary factor in the development of caries?

natural and free sugar

Sucrose can be broken down to…

Glucose and Fructose

Why is sucrose and its monosaccharides (glucose and fructose) more cariogenic than starches?

Because they enter the glycolytic pathway more rapidly and result in a more pronounced drop in pH

What causes the formation of dental plaque?

Presence of sucrose in lower concentration of calcium, inorganic phosphate, and fluoride, which are ions required to remineralize enamel and dentin

Why is vitamin D important in reduction of caries risk in children and infants?

Because vitamin D influences the regulation of calcium and phosphate metabolism

What is the bond between glucose and fructose monomers in sucrose?

Glycosidic linkage