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fatty acids
generate more energy than glucose or glycogen
biomolecules
consist fo carbon, hydroge, and oxygen
proteins, nucleic acid, carbohydrates, lipids
4 major biomolcules:
monomers or polymers
molecules fomed in living things come as ____
amino acid
are the building blocks of protein
signaling molcules (insulin receptor)
structural role (collagen)
mobility (actin)
defense (antibodies)
catalysts (enzymes)
5 functions of proteins:
adenine, cytosine, guanine, thymine
4 nucleic acids in DNA:
DNA (deoxyribonucleotide)
the nucleotide with a Hydrogen
RNA (ribonucleotide)
the nucleotide with an OH group
nucleic acids
are made up of mucleotides
glucose
is a monomer and the main sugar in the body (6 carbon sugar)
glycogen
is the storage form of glucose and is a polymer
homopolymer (glycogen)
only glucose together
triacylglycerol
fatty acids pH will go down if they are free floating so that have to be stored in the form of _____
mitochondria
have an outer membrane, inner membrane, and matrix; site of energy yielding oxidation reactions; has it own DNA
nucleus
location of main genome; site of most DNA and RNA synthesis
endoplasmic recticulm
continuous membrane throughout the cell; rough part is studded with ribosomes
ribosome
the site of protein synthesis
golgi apparatus
series of flatted membranes; involved in secretions of proteins from cells and in reactions that link sugars to other cellular components
lysosomes
membrane enclosed sacs containing hydrolytic enzymes
cell membrane
spearates the cell contents from the outside world; contents incluse organelles and the cytosol
cytoskeleton
hold organelles in place in the cell
provide energy
supply carbon for the synthesis of cell components
serve as a form of stored chemical enregy
form part of the structures of some cells and tissues
4 functions of carbohydrates (saccharides):
monosaccharide (glucose and fructose)
disaccharide (sucrose)
oligosaccharide (raffinose)
polysaccharide (starch, cellulose, glycogen)
4 classes of carbohydrates:
fructose
does not have its own metabolic pathway so it has to genter into the glycolytic pathway by getting phosphorlated
aldehyde (C with R, H, O)
ketone (C with 2R and O)
2 carbonyl groups:
monosaccharide
are the simplest sugars; can be aldehydes ot ketones that contain two or more alcohol groups; smallest ones are compoased of 3 carbons
triose
tetrose
pentose
hexose
number of carbon atoms names 3-6:
hemiacetal, hemiketal
the chemical basis for ring formations is that an aldehyde can reaction with an alcohol to form a ____ and a ketonw can reaction with an alcohol to form a ____
pyranose, pyran
in the case of glucose, the resulting intramolecular hemiacetal, a six carbon ring is called ___ because of its resemblance to ____
furanose, furan
in the case of the ketone furctose, the inramolecular hemiketal, a five carbon ring, is called a ___ because of its reseblance to ___
carbohydrates
can be modified by the addition of substituents other than hydroxyl groups; these modified ones are often expressed on cell surfaces
disaccharides
linkage of 2 sugars
maltose
is formed when two molecules of glucose are linked by an alpa-1,4-glycosidic bond
sucrose
a disaccharide made from glucose and fructose
lactose
a disaccharide made from glucose and glactose
sucrose
lactose
maltose
3 common disaccharides:
polysaccharide glycogen
is the storage form of glucose in animal cells
α-1, 4-glycosidic bonds; α-1, 6-glycosidic bonds
most glucose units in glycogen are lined by _____, with ranches formed by _____ every 10 glucose units
lipid
high solubility in non polar solvents and low solubility in H2O; fats, oils, waxes, some vitamins and hormones and most non protein components of membranes
major form of stored energy in biological system
major components of biological membranes
hormones
lipids are amphipathic molecules that can be:
fatty acids
common fuel
triacylclycerol
storage form of fatty acids
glycolipids
mambrane lipids composed of carbohydrates
steroids
polycyclic hydrocarbons with a variety of functions
laurate
a naturally occuring fatty acid with 12 carbons and no double bonds
myristate
a naturally occuring fatty acid with 14 carbons and no double bonds
palmitate
a naturally occuring fatty acid with 16 carbons and no double bonds
stearate
a naturally occuring fatty acid with 18 carbons and no double bonds
low melting temperature
high or low melting temperature for a fatty acid that is short and unsaturated
triacylglycerol
sotrage form of fat; contains 3 fatty acids and a glycerol
glycerol and sphingosine
2 backbones of phospholipids:
glycerophospholipids or phosphoglycerides
the backbone of phospholipids, glycerol can also be ____
sphingolipid
the backbone of phospholipids, sphingosine can also be ____
2 fatty acids
glycerol (a platforms)
phosphate
an alcohol at the end
phospholipids are composed of 4 components:
phosphoglycerides or phosphoglycerols
phospholipids with a glycerol platform
phosphatidate
the major phospholipids are derived from this
hormones
precursors of cholestrol
membrane components
steroids can be 3 things:
steroids
are made of 3 six carbon ring structures and 1 five carbon ring with an OH
membrane component
precursor of bile and hormones
absent in prokaryotes
maintains membrane fluidity
cholestrol can be 4 things:
enzymes
are proteins that increase the rate of reaction by lowering the energy of activation; are not altered or consumed suring reactions and reusable
all biochemical reactions
are enzyme catalyzed in the living organism
metabolism
diagnosis
therapeutics
digestive enzymes
4 functions of enzymes:
level of enzyme
____ in blood are of diagnostic importance (it is a good indicator in disease such as myocardial infarction)
enzymes
can be used therapeutically such as digestive enzymes
catalysts
accelerate the rate of the reaciton
Kcat
is the number of substrate molecules converted into product/ enzyme/ min
proteolytic enzymes
illustrate the range of enzyme specificity; catalyz the hydrolysis of peptide bonds
substrates
reactants in enzyme-catalyzed reaction
specificity
of an enzyme is due to the interaction between substrate with the enzyme
serine protease
also a trypsin; a family name where you have 3 amino acids in the clipping
oxidoreductase
catalyze oxidation-reduction reactions (dehydrogenases, reductases, oxidases)
NADH
is an electron carrier; hold the electrons that go into the electron transport chain
transferases
move functional groups between molecules (kinases, aminotransferases, thiolases)
kinases
do phosphorylation that come from ATP
hydrolyases
a major class of enzyme that requires water
lyases
remove atoms to form double bonds ot add atoms to double bonds (synthases, decarboxylases, dehydratases)