BIOLOGY PAPER 1 ALL CONTENT

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150 Terms

1
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Where is amylase produced?

Salivary glands, pancreas, small intestine

2
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Where is protease produced?

Stomach (pepsin), pancreas, small intestine

3
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Where is lipase produced?

Pancreas, small intestine

4
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What does protease break down and into what?

Breaks down proteins into amino acids

5
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What does lipase break down and into what?

Breaks down lipids into glycerol and fatty acids

6
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What is the optimum pH for pepsin?

pH 2 (acidic)

7
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What is the test for starch?

add Iodine solution using a pipet

turns blue-black if starch is present

8
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What is the test for sugars?

Benedict’s solution: heat in water bath, turns green/yellow/brick red depending on sugar concentration

9
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What is the test for proteins?

Biuret solution: turns from blue to purple if protein is present

10
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What is the test for lipids?

Sudan III or ethanol test: red layer on top (Sudan III) or cloudy emulsion (ethanol) if lipids are present

11
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Word equation for photosynthesis?

Carbon dioxide + water → glucose + oxygen

12
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Symbol equation for photosynthesis?

6CO₂ + 6H₂O → C₆H₁₂O₆ + 6O₂

13
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Word equation for aerobic respiration?

Glucose + oxygen → carbon dioxide + water

14
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Symbol equation for aerobic respiration?

C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O

15
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Word equation for anaerobic respiration in muscles?

Glucose → lactic acid

16
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Word equation for anaerobic respiration in plants?

Glucose → ethanol + carbon dioxide

17
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How are monoclonal antibodies made?

By combining a mouse B-lymphocyte

with a tumour cell

to make a hybridoma

that divides and produces identical antibodies

18
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Why are monoclonal antibodies useful?

They are specific to one binding site on one antigen so can target specific cells or substances

19
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How are monoclonal antibodies used in pregnancy tests?

They bind to the hormone hCG found in urine if pregnant

20
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How are monoclonal antibodies used in cancer treatment?

They can deliver drugs directly to cancer cells

or block growth signals

21
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How are monoclonal antibodies used in labs?

To locate specific molecules or measure levels of substances using markers

22
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How does vaccination prevent illness?

It stimulates white blood cells to produce antibodies, leading to immunity

23
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What is a double-blind trial?

Neither the patient nor the doctor knows who is receiving the drug or placebo, to prevent bias

24
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Why must drugs be tested?

To ensure they are safe, effective, and have the correct dosage

25
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What is a placebo and why is it used?

A dummy treatment used to compare effects in clinical trials

26
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What causes antibiotic resistance?

Overuse and misuse of antibiotics, allowing resistant bacteria to survive and reproduce

27
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What is transpiration?

The loss of water vapour from the leaves of a plant through the stomata

28
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How do guard cells work?

They open and close stomata to control water loss and gas exchange

29
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What are stomata?

Pores in the leaf that allow gas exchange

30
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Why is the palisade layer good for photosynthesis?

It has many chloroplasts and is near the top of the leaf to receive maximum light

31
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How does a vaccine lead to immunity?

White blood cells produce memory cells that respond faster to future infection

32
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What is the function of the nucleus?

It contains genetic material that controls the activities of the cell.

33
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What is the function of mitochondria?

They are the site of aerobic respiration, which releases energy.

34
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Compare prokaryotic and eukaryotic cells.

Prokaryotic cells lack a nucleus and membrane-bound organelles; eukaryotic cells have both.

35
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Why do root hair cells have a large surface area?

To increase the rate of absorption of water and mineral ions from the soil.

36
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Describe the process of mitosis.

Mitosis is cell division that produces two identical daughter cells for growth and repair.

<p>Mitosis is cell division that produces two identical daughter cells for growth and repair.</p>
37
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What is the purpose of stem cells?

Stem cells can differentiate into different types of cells and are used in development and repair.

38
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Where are adult stem cells found?

In bone marrow.

39
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What are the ethical issues surrounding stem cell use?

Some people object to the use of embryos, believing life begins at conception.

40
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How is diffusion different from active transport?

Diffusion is passive; active transport requires energy to move substances against a concentration gradient.

41
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Why does temperature affect diffusion?

Higher temperatures increase kinetic energy and speed up particle movement.

42
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What is the function of enzymes?

To catalyse biological reactions by lowering activation energy.

43
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How does pH affect enzyme activity?

Each enzyme has an optimum pH; too high or too low denatures the enzyme.

44
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What happens to an enzyme when it denatures?

The active site changes shape and can no longer bind to the substrate.

45
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What does amylase do?

Breaks down starch into sugars.

46
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Where is bile produced and what does it do?

Produced in the liver; neutralises stomach acid and emulsifies fats.

47
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Name the four components of blood.

Red blood cells - carries o2 around the body

white blood cells - defending body against infection and disease

platelets - blood clotting

plasma - liquid transportation

48
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What is the function of red blood cells?

Transport oxygen using haemoglobin.

49
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How are arteries different from veins?

Arteries have thick muscular walls and carry blood away from the heart

Veins have valves and carry blood to the heart.

50
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What is coronary heart disease?

A condition where the coronary arteries are narrowed or blocked, reducing blood flow to the heart.

51
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Describe how stents work.

Stents are tubes inserted into arteries to keep them open and improve blood flow.

52
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What is a pathogen?

A microorganism that causes disease.

53
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Name four types of pathogens.

Bacteria, viruses, fungi, protists.

54
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How do viruses make you feel ill?

They reproduce inside cells, causing cell damage.

55
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How does the body defend itself against pathogens?

Skin, mucus, stomach acid, white blood cells (phagocytosis, antibodies, antitoxins).

56
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What is the purpose of vaccination?

To stimulate the immune system to produce antibodies without causing illness.

57
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How do antibiotics work?

They kill or inhibit the growth of bacteria.

58
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Why don’t antibiotics work on viruses?

Viruses reproduce inside host cells, which antibiotics can't target without harming the host.

59
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What is antibiotic resistance?

When bacteria evolve and are no longer killed by antibiotics.

60
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What are monoclonal antibodies?

Identical antibodies produced from a single clone of cells, used in medicine for diagnosis and treatment.

61
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What is a placebo?

A substance with no therapeutic effect, used as a control in testing new drugs.

62
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What is the word equation for photosynthesis?

Carbon dioxide + water → glucose + oxygen

63
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Where does photosynthesis occur?

In the chloroplasts of plant cells.

64
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What are the limiting factors of photosynthesis?

Light intensity, carbon dioxide concentration, temperature.

65
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Why is photosynthesis important?

It produces oxygen and glucose, essential for life on Earth.

66
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What is the word equation for aerobic respiration?

Glucose + oxygen → carbon dioxide + water (+ energy)

67
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What is anaerobic respiration?

Respiration without oxygen, producing less energy.

68
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How is lactic acid removed from muscles?

It is transported to the liver and broken down.

69
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Why does heart rate increase during exercise?

To supply muscles with more oxygen and glucose for respiration.

70
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What is metabolism?

The sum of all chemical reactions in the body.

71
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Give an example of a metabolic reaction.

Converting glucose to starch in plants.

72
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What is the function of the cell membrane?

It controls what enters and leaves the cell.

73
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What are plasmids?

Small loops of DNA found in bacterial cells.

74
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What is the role of chloroplasts?

To carry out photosynthesis using light energy.

75
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What does the term 'cell differentiation' mean?

The process by which a cell changes to become specialized for its function.

76
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Why is the electron microscope important in biology?

It allows higher magnification and resolution than a light microscope, revealing more detail.

77
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What are the three stages of the cell cycle?

Interphase, mitosis, and cytokinesis.

78
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Give one use of therapeutic cloning.

It can be used to generate stem cells

that are genetically identical to the patient.

79
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What is the function of xylem vessels?

To transport water and mineral ions from roots to leaves.

80
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What is translocation?

The movement of sugars through phloem from sources to sinks.

81
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How does the structure of alveoli help gas exchange?

Large surface area

thin walls

good blood supply increase diffusion efficiency.

82
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What enzyme breaks down proteins?

Protease.

83
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Why is the heart called a double circulatory system?

It has two circuits: one to the lungs and one to the rest of the body.

84
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How do artificial pacemakers work?

They send electrical impulses to control heart rate.

85
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What is cancer?

Uncontrolled cell division that forms a tumor, which can be benign or malignant.

86
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How is measles spread?

Through droplets from coughs and sneezes.

87
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What is malaria caused by?

A protist spread by mosquitoes.

88
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Why is hygiene important in disease prevention?

It reduces the spread of pathogens.

89
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What is herd immunity?

When enough of a population is vaccinated to stop the spread of a disease.

90
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What is the first stage of drug testing?

Preclinical testing on cells, tissues, and animals.

91
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How are monoclonal antibodies used in pregnancy tests?

They bind to the hormone hCG found in urine during pregnancy.

92
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What is the inverse square law in photosynthesis?

Light intensity ∝ 1/distance², meaning light intensity decreases with distance squared.

93
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How is glucose used by plants?

For respiration

making cellulose

making amino acids

storing as starch.

94
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What is oxygen debt?

The extra oxygen needed after exercise to remove lactic acid and repay the deficit.

95
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How does temperature affect respiration?

Higher temperatures increase enzyme activity up to an optimum; too high denatures enzymes.

96
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What is the method for the food tests practical?
Prepare food sample and transfer to test tube; add Benedict's for sugar (heat), iodine for starch, Biuret for protein, and Sudan III or ethanol for lipids. Observe colour changes.
97
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What is a positive result for Benedict’s test for sugar?
Green, yellow, or brick-red depending on concentration
98
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What is a positive result for iodine test for starch?
Blue-black
99
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What is a positive result for Biuret test for protein?
Purple
100
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What is a positive result for Sudan III test for lipids?
Red layer on top