HIERARCHICAL LAYERS OF 3D GENOME ORGANISATION (Page 10)

0.0(0)
Studied by 0 people
call kaiCall Kai
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/4

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 1:55 PM on 6/19/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai

No analytics yet

Send a link to your students to track their progress

5 Terms

1
New cards

; [What is Hi-C and what does it reveal?]

a genome-wide derivative of chromatin capture

2
New cards

WHAT DOES HI-C REVEAL

each interaction in the nuclear space,

3
New cards

WHAT DOES HI-C RESULT IN

a 2D heat map where each data point indicates the frequency of interaction between two points in the genome.

4
New cards

; [What are the hierarchical layers of 3D genome organization from largest to smallest?]

DNA exists in chromosome territories,

which are further divided into chromatin compartments A and B.

Finer-scale structures such as TADs and DNA loops within them are regulated by cohesin and CTCF.

5
New cards

; [What genomic processes are influenced by chromatin architecture?]

Transcription, DNA replication, and DNA repair.