601 Quiz 1 - Anxiety/Depression

sertraline brand name

Zoloft

drug class of sertraline, fluoxetine

SSRI

name 5 indications that are shared amongst this weeks drugs

MDD, GAD, OCD, PTSD, SAD

common side effects of sertraline

GI upset, fatigue

generic name of Zoloft

sertraline

brand name of fluoxetine

Prozac

generic name of Prozac

fluoxetine

common side effects of fluoxetine

GI upset (nausea), insomnia, somnolence

what BBW is on all antidepressants

increased risk of suicide ideation

what two drugs this week do not have a BBW

buspirone, pregabalin

brand name of vilazodone

Viibryd

generic name of Viibryd

vilazodone

drug class of vilazodone

serotonin modulators; SSRI-like

only FDA indication of vilazodone

MDD

MOA of vilazodone

inhibits SERT and partial agonist of 5-HT1A

common side effects of vilazodone

GI upset

brand name of venlafaxine

Effexor

generic name of Effexor

venlafaxine

drug class of venlafaxine, duloxetine

SNRI

what is a key adverse effect of venlafaxine

dose-related hypertension

what are some unique indications for duloxetine

neuropathic pain, fibromyalgia, stress urinary incontinence

brand name of duloxetine

Cymbalta

generic name of Cymbalta

duloxetine

brand nameS of bupropion

Wellbutrin; Zyban

what is a unique indication for wellbutrin

smoking cessation

common side effects of bupropion

tachycardia, headache, insomnia, dry mouth, seizures (dose-related)

drug class of bupropion

NDRI

brand name of buspirone

Buspar

drug class of buspirone

non-benzodiazepine anxiolytic

MOA of buspirone

5-HT1A partial agonist

side effects of buspirone

dizziness, somnolence

brand name of mirtazapine

Remeron

generic name of Remeron

mirtazapine

drug class of mirtazapine

serotonin modulator; a2 antagonist

side effects of mirtazapine

weight gain, constipation, somnolence

brand name of esketamine

Spravato

generic name of Spravato

esketamine

drug class of esketamine

NMDA antagonist

FDA indication for esketamine

treatment-resistant depression

BBW of esketamine (5)

sedation, dissociation, respiratory depression, misuse/abuse, suicide ideation

brand name of pregabalin

Lyrica

generic name of Lyrica

pregabalin

drug class of pregabalin

GABA-mediated anticonvulsant

what voltage gated channel does pregabalin target

CaV

common side effects of pregabalin

peripheral edema, weight gain, somnolence, dizziness, tremor, fatigue