Simple cyst (2 layers of epithelial cells)

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7 Terms

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Simple Cysts - Pathogenesis (2)

  1. Hormonal-induced changes in breast tissue with the menstrual cycle

  2. Fluid accumulation and distension of the TDLU

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Simple Cyst - Histology (2)

  1. Secretions from the epithelial cells

    can calcify

    1. Microcalcifications

  2. Apocrine metaplasia

    1. Cells are large with ‘snout’ and more pink granular cytoplasm

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Characteristic ultrasound of a simple cyst

  1. Round or ovoid structure

  2. Regular/ discrete boarder

  3. Black/ filled with fluid

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Development of fibrosis associated with cysts (3)

  1. Cyst ruptures

  2. Inflammation → Fibrosis

Called Fibrocystic changes

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Cysts - Gross Morphology (2)

  1. Blue dome cyst

  2. Patchy white area - fibrosis

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Cysts – Symptoms (5)

  1. Firm, smooth, discrete mass

  2. May be solitary or multiple

  3. Breast feels lumpy bumpy but firm (with fibrosis

  4. Premenstrual enlargement and postmenstrual involution

  5. May be tender

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Cysts – Incidence

Any age - Not over 50 because no more hormonal changes.