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the primary purpose of the cardiovascular system
deliver adequate levels of oxygen and remove wastes from body tissues
in order to meet the increased oxygen demands of muscle during exercise, two major adjustments in blood flow must be made
an increase in cardiac output and a redistribution of blood flow form inactive tissues to skeletal muscles
all gas exchange between the vascular system and tissues occurs in
capillaries
backflow of blood form the arteries into the heart ventricles is prevented by the
semilunar valves
the muscle of the heart is referred to as the
myocardium
electrical impulses are conducted between heart muscle cells by
intercalated discs
the contraction phase of the heart is called
systole
in a healthy heart, the time spent in systole is generally ____________ diastole
shorter than
during exercise, the time spent in diastole and systole
is decreased, with the greatest decrease occurring in diastole
the difference between systolic and diastolic blood pressure is called the
pulse pressure
the normal pacemaker of the heart is the
Sinoatrial node
the _________ represents ventricular repolarization during a recording of the electrical activity (i.e., ECG) of the heart
T wave
withdrawal of parasympathetic influence of the heart results in
an increase in heart rate
the cardiovascular control center is located in the
medulla oblongata
the fact that an increase in end diastolic ventricular volume increases the stroke volume of the heart is an illustration of the
Frank-Starling Law of the Heart
the increase in cardiac output that occurs during exercise is due to
both an increase in mean arterial pressure and a decrease in vascular resistance
the most important variable that determines resistance blood flow is
the diameter of the blood vessel
the relationship between cardiac output and metabolic rate is
linear and positively correlated
in most subjects, stroke volume continues to increase during incremental exercise up to approximately
40% of Vo2 max
the age dependent decrease in maximal heart rate can be estimated via the karvonen formula
HR max = 220-age (years)
autoregulation of blood flow to contracting muscles during exercise is due to
locally produced factors such as nitric oxide, prostaglandins, and adenosine
most of the increase in mean arterial blood pressure that occurs during dynamic (isotonic) incremental exercise is due to
the increase in systolic blood pressure
sympatholysis refers to
local inhibition of sympathetic-induced vasoconstriciton
a local increase in the nitric oxide concentration around arterioles would result in
vasodilation
the arterial-venous oxygen difference
increases as a function of exercise intensity
the relationship between oxygen uptake, cardiac output, and the arterial-venous oxygen difference is described mathematically by the
Fick Equation
the metabolic demand of the heart can be estimated by
1) the rate-pressure product
2) the double product
3) multiplying heart rate by systolic blood pressure
the greatest resistance to blood flow is in the
arterioles
the central command theory of cardiovascular control proposes that initial signal to the cardiovascular control centers comes from
higher brain centers
which of the following is the correct order of events pertaining to contraction of the left ventricle
the bundle branches depolarize, the ventricle contracts, the ventricular pressure increases, and blood exists the ventricle
which of the following most accurately describes changes in autonomic control of heart rate during incremental exercise (from rest to VO2 max)?
PNS withdrawal is followed by SNS outflow
which of the following factors can decrease blood pressure?
systemic vasodilation
skeletal and cardiac muscle are similar in which of the following ways?
both muscles are composed of striated fibers containing actin and myosin
which of the following is NOT a mechanism for increasing venous return during exercise?
an increase in stroke volume
which of the following represents the correct order of events of the flow of blood after it leaves the left ventricle and before it returns to the right atrium?
blood flows through the aorta, oxygen moves out of the capillaries, blood flows through the venules, blood enters the veins
atrial repolarization occurs during which phase of the cardiac cycle as observed on an ECG?
the QRS complex
according to the Fick equation, if cardiac output doubles during exercise and the arterial-mixed venous oxygen difference remains constant, body oxygen consumption would
increase by 100%
which of the following statements about beta-adrenergic blocking medications are true?
1) beta blocking drugs reduce heart rate during exercise
2) beta blockages reduces the vigor of ventricular contraction
3) beta blocking drugs compete with epinephrine and norepinephrine for beta-adrenergic receptors in the heart
which of the following factors contribute to "fine-tuning" of cardiovascular control during exercise?
1) muscle chemoreceptors
2) baroreceptors
3) muscle mechanoreceptors
Which of the following factors has the greatest influence on blood flow to a skeletal muscle during exercise?
diameter of the arterial blood vessels leading to the muscle
Which of the following statements about heart rate variability (HRV) is NOT true?
HRV decreases in response to regular aerobic exercise training.
If a person with ischemic heart disease experiences chest pain when their double product exceeds 20,000, which of the following combinations will produce angina?
HR = 150, BP = 150/80
Which of the following would not result in an increase in stroke volume during exercise?
an increase in afterload
In the transition from rest to exercise, what is the distribution of cardiac output to the heart?
the % of cardiac output is unchanged, but the volume of blood increases