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Immunoglobulins and chemokines
A neurotrophin
the process where new branches form on an axon to attach to vacant receptors on a postsynaptic neuron.
neurotrophins
chemical that promotes the survival of neurons. If a neuron is not exposed to neurotrophins, then it undergoes apoptosis
Apoptosis
a type of cell death
nerve growth factor (NGF)
a protein promotes the survival and growth of axons
sex-linked genes
x-linked genes
sex-limited genes
genes that are limited to a particular sex
four central nervous system that develop
hindbrain, midbrain, forebrain, and spinal cord
Fetal Alcohol Syndrome
hyperactivity and impulsivity
difficulty maintaining attention
mental retardation
motor problems and heart defects
facial abnormalities
fine-tuning by experience
axons and dendrites modify throughout life
Blind brain adaptions
increased activation in the occipital cortex
use occipital lobe. to differentiate between tactical stimulaiton and braille symbols
focal hand dystonia
excessive practice leads to clumsiness, fatigue, and involuntary movement because of extensive reorganization of sensory thalamus and cortex so that the responses of each finger overlaps with another.
ischemic stroke
most common caused by blood clot or obstruction
hemorrhage
less frequent kind of stroke caused by a ruptured artery that floods neurons with excess blood, calcium, oxygen, and other chemicals.
edema
As a result of a stroke, there is an accumulation of fluid in brain that increases pressure on the grain and increases probability of strokes
disruption of sodium-potassium pump
leads to accumulation of potassium ions inside the neuron.
immediate medicinal treatment for strokes
tPA: medication that breaks up blood clots that must be administered quickly
cooling brain
minimizes damage after an ischemic stroke by reducting overstimulation, apoptosis, and inflammation
diaschisis
decreased activity of surviving neurons
after a stroke, destroyed cell bodies cannot be replaced
but damaged axons do grow back by following the myelin sheath.
axon sprouting
collateral sprouts renew branches from non-damaged axons that attach to vacant receptors, and cells that have lost their source of innervation release neurotrophins that induce axons to form collateral sprouts
denervation supersensitivity
heightened sensitivity to neurotransmitter after the destruction of an incoming axon. this can cause chronic pain
phantom limbs
cortex reorganizes itself after amputation by being responsive to other parts of the body