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Phosphorus
Is the major anion in the intracellular fluid which is inversely related to calcium
bones, teeth
intracellular fluid
Phosphorus
Distributed as 85% in _ and _, 15% in _ _
neuromuscular activity
ATP- ADP, vitamin B
carbohydrates, proteins, fats
Functions
Role in _ _
Durability of bones and teeth – helps in the formation of _-_, _ _ utilization, transmission of hereditary traits
Metabolism of _, _, and _ and in the acid-base balance
kidneys
GI secretions
Excretions
Majority of this electrolyte is being excreted by body through the _ (90%) and only 10% by the _ _
Parathyroid Hormone
Regulation
Lowers Phosphate concentration by increasing renal excretion
Vitamin D
Regulation
Increases Phosphate concentration by reabsorption in the kidney
Growth Hormone
Regulation
Increases Phosphate concentration by regulation of skeletal growth
Alcohol abuse - most common
Vitamin D deficiency
Hyperthyroidism
Hypophosphatemia (3)
Renal failure
Increased phosphate intake
Increased cellular phosphate release
Increased breakdown of cells
Hyperphosphatemia (4)
Serum
Plasma (lithium heparin)
24 hour urine
Specimens (3)
Oxalate, citrate, EDTA
false increased
Interferences
Do not use _, _, _ which tends to falsely decrease the level of phosphorus
Do not use hemolyzed specimen that gives _ _ result
Fiske-Subbarow Method
Methods of Measurement
Conversion of inorganic phosphate to heteromolybdenum blue by reacting with ammonium molybdate
5-Minute Test Micro Method
Methods of Measurement
Second method
600
Mix well and read at _ nm against water blank after five minutes
5
Computation factor (mg/dL)
0.324 = mmol/L
Conversion to SI unit (mmol/L) for phosphorus levels.
2.5-4.5 mg/dL
Normal Range
Conventional Unit
Adult
0.81-1.46 mmol/L
Normal Range
SI Unit
Adult
3.5-6.5 mg/dL
Normal Range
Conventional Unit
Infant & Children
1.13-2.11 mmol/L
Normal Range
SI Unit
Infant & Children
Photometric UV test
Method in lab manual