PHOSPHORUS

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21 Terms

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Phosphorus

Is the major anion in the intracellular fluid which is inversely related to calcium

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bones, teeth

intracellular fluid

Phosphorus

Distributed as 85% in _ and _, 15% in _ _

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neuromuscular activity

ATP- ADP, vitamin B

carbohydrates, proteins, fats

Functions

Role in _ _

Durability of bones and teeth – helps in the formation of _-_, _ _ utilization, transmission of hereditary traits

Metabolism of _, _, and _ and in the acid-base balance

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kidneys

GI secretions

Excretions

Majority of this electrolyte is being excreted by body through the _ (90%) and only 10% by the _ _

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Parathyroid Hormone

Regulation

Lowers Phosphate concentration by increasing renal excretion

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Vitamin D

Regulation

Increases Phosphate concentration by reabsorption in the kidney

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Growth Hormone

Regulation

Increases Phosphate concentration by regulation of skeletal growth

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Alcohol abuse - most common

Vitamin D deficiency

Hyperthyroidism

Hypophosphatemia (3)

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Renal failure

Increased phosphate intake

Increased cellular phosphate release

Increased breakdown of cells

Hyperphosphatemia (4)

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Serum

Plasma (lithium heparin)

24 hour urine

Specimens (3)

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Oxalate, citrate, EDTA

false increased

Interferences

Do not use _, _, _ which tends to falsely decrease the level of phosphorus

Do not use hemolyzed specimen that gives _ _ result

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Fiske-Subbarow Method

Methods of Measurement

Conversion of inorganic phosphate to heteromolybdenum blue by reacting with ammonium molybdate

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5-Minute Test Micro Method

Methods of Measurement

Second method

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600

Mix well and read at _ nm against water blank after five minutes

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5

Computation factor (mg/dL)

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0.324 = mmol/L

Conversion to SI unit (mmol/L) for phosphorus levels.

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2.5-4.5 mg/dL

Normal Range

Conventional Unit

Adult

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0.81-1.46 mmol/L

Normal Range

SI Unit

Adult

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3.5-6.5 mg/dL

Normal Range

Conventional Unit

Infant & Children

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1.13-2.11 mmol/L

Normal Range

SI Unit

Infant & Children

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Photometric UV test

Method in lab manual