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Vocabulary flashcards covering the cell cycle, DNA replication, and protein synthesis.
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Cell cycle
The series of stages that cells go through to divide, including interphase and the mitotic (M) phase.
Interphase
Growth and metabolic activities; DNA replication occurs; consists of G1, S, G2 (G0 for cells that permanently cease dividing).
G1
First gap phase; vigorous growth and metabolism.
S (synthesis)
DNA replication occurs during this phase.
G2
Second gap phase; preparation for division and final growth.
G0
Phase in which cells permanently cease dividing.
Semiconservative replication
DNA replication in which each new DNA molecule has one old strand and one new strand.
Replication fork
The point where DNA strands separate and replication occurs.
DNA replication
The process of copying the cell’s DNA prior to division.
Nucleotide
The basic unit of DNA and RNA, composed of a sugar, phosphate, and a base.
Deoxyribose
The sugar component of DNA.
Phosphate
Part of the DNA backbone linking sugars together.
Adenine (A)
DNA base that pairs with thymine (and with uracil in RNA).
Thymine (T)
DNA base that pairs with adenine.
Cytosine (C)
DNA base that pairs with guanine.
Guanine (G)
DNA base that pairs with cytosine.
Complementary base pairing
A pairs with T (or U in RNA); C pairs with G.
Double helix
The twisted ladder structure of DNA formed by base pairing.
Mitosis
Nuclear division producing two identical nuclei; stages: prophase, metaphase, anaphase, telophase.
Prophase
First stage of mitosis; chromosomes condense, nucleolus disappears, spindle forms.
Metaphase
Chromosomes align at the metaphase plate; spindle fibers attach to centromeres.
Anaphase
Sister chromatids split and move toward opposite poles.
Telophase
Nuclei form around each set of chromosomes; chromosomes de-condense.
Cytokinesis
Division of cytoplasm; contractile ring forms cleavage furrow; two daughter cells result.
M phase
Mitotic phase; includes mitosis and cytokinesis.
Checkpoints
Control points (e.g., G1 checkpoint) that regulate progression of the cell cycle.
Messenger RNA (mRNA)
RNA that carries genetic information from DNA to ribosomes for protein synthesis; produced by transcription.
Ribosomal RNA (rRNA)
Structural component of ribosomes, where protein synthesis occurs.
Transfer RNA (tRNA)
Carries amino acids and contains anticodons that pair with mRNA codons during translation.
Transcription
Process of copying DNA into an mRNA sequence.
Translation
Process of decoding mRNA to synthesize a polypeptide (protein).
Codon
A three-base sequence in mRNA that codes for an amino acid or a stop signal.